392287-03-5
Chemical Structure
Cyclotriazadisulfonamide hydrochloride
Synonym(s): CADA hydrochloride
- CAS No.: 392287-03-5
- Formula:C31H40ClN3O4S2
- Molecular Weight:618.25
SMILES: O=S(C1=CC=C(C)C=C1)(N2CC(CN(S(=O)(C3=CC=C(C)C=C3)=O)CCCN(CCC2)CC4=CC=CC=C4)=C)=O.Cl
Biological Activity: Cyclotriazadisulfonamide (CADA) hydrochloride is a specific CD4-targeted HIV entry inhibitor with activity against HIV-1 replication. Cyclotriazadisulfonamide hydrochloride can specifically downregulate the expression of CD4 receptors on the cell surface, effectively inhibiting HIV transmission. Cyclotriazadisulfonamide hydrochloride can inhibit HIV-1(NL4.3) and SIV(mac251), and has a synergistic effect when used in combination with cellulose acetate (CAP). Cyclotriazadisulfonamide hydrochloride can also be used as a microbial gel formulation to maintain CD4 downregulation and antiviral activity, and is a broad-spectrum anti-HIV agent.
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Cyclotriazadisulfonamide hydrochloride | Cyclotriazadisulfonamide (CADA) hydrochloride is a specific CD4-targeted HIV entry inhibitor with activity against HIV-1 replication. Cyclotriazadisulfonamide hydrochloride can specifically downregulate the expression of CD4 receptors on the cell surface, effectively inhibiting HIV transmission. Cyclotriazadisulfonamide hydrochloride can inhibit HIV-1(NL4.3) and SIV(mac251), and has a synergistic effect when used in combination with cellulose acetate (CAP). Cyclotriazadisulfonamide hydrochloride can also be used as a microbial gel formulation to maintain CD4 downregulation and antiviral activity, and is a broad-spectrum anti-HIV agent. | |||||||||||||||||||||
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