1. Anti-infection
  2. Reverse Transcriptase
    HIV
  3. Loviride

Loviride (Synonyms: R 89439)

Cat. No.: HY-15355
Handling Instructions

Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells.

For research use only. We do not sell to patients.

Loviride Chemical Structure

Loviride Chemical Structure

CAS No. : 147362-57-0

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Description

Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells[1].

IC50 & Target

IC50: 0.3 µM (Reverse transcriptase)[1]

In Vitro

Loviride (0.01 µM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC50s of 85.5, 7.4 µM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 µM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

351.23

Formula

C₁₇H₁₆Cl₂N₂O₂

CAS No.

147362-57-0

SMILES

O=C(N)C(NC1=C(C(C)=O)C=CC(C)=C1)C2=C(Cl)C=CC=C2Cl

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Loviride
Cat. No.:
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Loviride

Cat. No.: HY-15355