112190-24-6
Chemical Structure
U-75875
- CAS No.: 112190-24-6
- Formula:C45H61N7O7
- Molecular Weight:812.01
IUPAC Name: (2R,3R,4R,5S)-5-((S)-3-(1H-imidazol-5-yl)-2-(2-(naphthalen-1-yloxy)acetamido)propanamido)-6-cyclohexyl-3,4-dihydroxy-2-isopropyl-N-((2S,3S)-3-methyl-1-oxo-1-((pyridin-2-ylmethyl)amino)pentan-2-yl)hexanamide
InChIKey: ZTKCGLWIXHAITR-JIFWBGJESA-N
SMILES: O=C(NCC1=CC=CC=N1)[C@H]([C@@H](C)CC)NC([C@H](C(C)C)[C@@H](O)[C@H](O)[C@H](CC2CCCCC2)NC([C@H](CC3=CN=CN3)NC(COC4=CC=CC5=C4C=CC=C5)=O)=O)=O
Biological Activity: U-75875 is a HIV-1 protease inhibitor. U-75875 can block Gag-Pol protein processing and viral maturation and replication. U-75875 can be used for the research of infection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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U-75875 | U-75875 is a HIV-1 protease inhibitor. U-75875 can block Gag-Pol protein processing and viral maturation and replication. U-75875 can be used for the research of infection. | |||||||||||||||||||||
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References
- [1]. Martin LN, et al. Effects of U-75875, a peptidomimetic inhibitor of retroviral proteases, on simian immunodeficiency virus infection in rhesus monkeys. Antimicrob Agents Chemother. 1994 Jun;38(6):1277-83. [Content Brief]
- [2]. Peterson PK, et al. Anti-human immunodeficiency virus type 1 activities of U-90152 and U-75875 in human brain cell cultures. Antimicrob Agents Chemother. 1994 Oct;38(10):2465-8. [Content Brief]
