178820-70-7
Chemical Structure
AQ148
- CAS No.: 178820-70-7
- Formula:C30H37N3O4
- Molecular Weight:503.63
InChIKey: VFHVMNORSGLKBR-MKWATWPISA-N
SMILES: C[N@+](CC1=CC=CC=C1)(C[C@H]([O-])C(NC(OC(C)(C)C)=O)CC2=CC=CC=C2)NC(C3=CC=CC=C3)=O
Biological Activity: AQ148 is a HIV-1 protease inhibitor (Ki=137 nM). The IC50 values ??of AQ148 for the inhibition of HIV-1, HIV-2 and SIV aspartic proteases are 1.5 μM, 3.4 μM and 5 μM, respectively[1].
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AQ148 | AQ148 is a HIV-1 protease inhibitor (Ki=137 nM). The IC50 values ??of AQ148 for the inhibition of HIV-1, HIV-2 and SIV aspartic proteases are 1.5 μM, 3.4 μM and 5 μM, respectively. | |||||||||||||||||||||
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Keywords