Norviburtinal 

Norviburtinal is a non-selective cytotoxic and pro-angiogenic agent. Norviburtinal has an IC₅₀ of 3.25 μg/mL on G361 melanoma cells and an effective concentration of 50 μg/mL on zebrafish embryos. Norviburtinal promotes capillary sprout formation in zebrafish subintestinal vessels (SIV) and has both cytotoxic and pro-angiogenic activities. Norviburtinal can be used in research on promoting angiogenesis related to melanoma, lung cancer, and wound healing^[1][2].

Norviburtinal has an IC₅₀ of 3.25 μg/mL on G361 melanoma cells and an effective concentration of 50 μg/mL on zebrafish embryos^[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

146.14

C₉H₆O₂

85051-41-8

O=CC1=CC=C2C=COC=C12

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Liu CL, et al. Bioassay-guided isolation of norviburtinal from the root of Rehmannia glutinosa, exhibited angiogenesis effect in zebrafish embryo model. J Ethnopharmacol. 2011 Oct 11;137(3):1323-7.  [Content Brief]

  [2]. Jackson SJ, et al. In vitro cytotoxicity of norviburtinal and isopinnatal from Kigelia pinnata against cancer cell lines. Planta Med. 2000 Dec;66(8):758-61.  [Content Brief]