8 Results for "

Thalidomide-NH-CH2-COOH

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Thalidomide-NH-CH2-COOH" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-131717
CAS No.: 927670-97-1
Purity:  98.07%
Research Areas:  

Cancer

Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937) .
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Cat. No.: HY-122830
CAS No.: 2366132-45-6
Purity:  98.72%
Target:  

PROTACs Btk NF-κB

Research Areas:  

Cardiovascular Disease Cancer

DD-03-171 is a PROTAC BTK degrader. DD-03-171 inhibits mantle cell lymphoma (MCL) cell proliferation (IC50 = 5.1 nM) and prolongs the survival of mice bearing a lymphoma PDX model by degrading BTK, IKFZ1, and IKFZ3. DD-03-171 also inhibits platelet function and thrombosis. (Pink: BTK ligand 9 (HY-168292); Black: linker (HY-28875); Blue: Thalidomide-NH-CH2-COOH (HY-131717)) [2] .
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Cat. No.: HY-131717A
CAS No.: 2377032-39-6
Research Areas:  

Cancer

Thalidomide-NH-CH2-COOH TFA is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH TFA can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937) .
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Cat. No.: HY-P1170
CAS No.: 2703746-32-9
Synonyms: Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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Cat. No.: HY-P10964
CAS No.: 2802416-72-2
Target:  

GHSR

Research Areas:  

Endocrinology

Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research on diseases caused by excessive growth hormone secretion, such as acromegaly .
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Cat. No.: HY-P5568
CAS No.: 152835-17-1
Synonyms: RP 71955
Target:  

HIV

Research Areas:  

Infection

RP 71955 is an antimicrobial peptide against HIV-1 .
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Cat. No.: HY-P12134
CAS No.: 3056608-43-3
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Zormapatide is a gastric inhibitory polypeptide (GIP) receptor agonist peptide. Zormapatide contains 2-methylalanine residues and an N 6-[N-(19-carboxynonadecanoyl)-L-γ-glutamyl-L-lysyl] modification. Zormapatide is applicable to the research of diabetes and metabolic diseases .
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Cat. No.: HY-P12133
CAS No.: 3080063-21-1
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Tapimtrutide is a gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Tapimtrutide can be used for the research of diabetes .
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