2377032-39-6
2377032-39-6
Chemical Structure
Thalidomide-NH-CH2-COOH TFA
- CAS No.: 2377032-39-6
- Formula:C17H14F3N3O8
- Molecular Weight:445.30
InChIKey: DVLANAHULWVZNM-UHFFFAOYSA-N
SMILES: O=C(O)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(C(F)(F)F)O
Biological Activity: Thalidomide-NH-CH2-COOH TFA is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH TFA can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937)[1].
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Thalidomide-NH-CH2-COOH TFA | Thalidomide-NH-CH2-COOH TFA is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH TFA can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937). | |||||||||||||||||||||
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References
Keywords
