927670-97-1
927670-97-1
Chemical Structure
Thalidomide-NH-CH2-COOH
- CAS No.: 927670-97-1
- Formula:C15H13N3O6
- Molecular Weight:331.28
IUPAC Name: (2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine
InChIKey: LRGLFYOYKPSPJQ-UHFFFAOYSA-N
SMILES: O=C(O)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity: Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thalidomide-NH-CH2-COOH | 98.07% | Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937). | ||||||||||||||||||||
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References
Keywords
