3 Results for "

U87EGFRvIII cells

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "U87EGFRvIII cells" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-116035
CAS No.: 25990-37-8
Purity:  99.79%
Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .
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Cat. No.: HY-146275
CAS No.: 2416049-12-0
Target:  

LXR

Research Areas:  

Cancer

LXRβ agonist-3 (compound 4-13) is a potent and selective LXRβ (liver X receptor β) agonist, with an EC50 of 0.095 μM. LXRβ agonist-3 efficiently inhibits U87EGFRvIII cell, with an IC50 of 3.75 μM. LXRβ agonist-3 shows antitumor activity, and can inhibit glioblastoma .
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Cat. No.: HY-116035R
CAS No.: 25990-37-8
Nimbolide (Standard) is the analytical standard of Nimbolide. This product is intended for research and analytical applications. Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .
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