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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
VHL-defective
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "VHL-defective" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-B2171A
CAS No.: 52794-97-5
Synonyms: Carminomycin hydrochloride; Carminomicin I hydrochloride
Category:
Infection Quinones Microorganisms Anthraquinones Phenols Polyphenols Disease Research Fields
Target:
1
Category:
Infection Quinones Microorganisms Anthraquinones Phenols Polyphenols Disease Research Fields
Target:
Target:
Research Areas:
MS181 is a BMI1 and RING1B degrader with antiproliferative activity. MS181 induces degradation via an EED-, CRBN-, and ubiquitin-proteosome system-dependent pathway, with preferential targeting over PRC2 components. MS181 acts in VHL-defective cancer cells. MS181 serves as a chemical biology tool to study PRC1 roles in cancer. MS181 can be used for the research of myelogenous leukemia, renal cell carcinoma, metastatic prostate cancer, triple negative breast cancer .
Cat. No.: HY-B2171AR
CAS No.: 52794-97-5
Synonyms: Carminomycin hydrochloride (Standard); Carminomicin I hydrochloride (Standard)
Category:
Target:
-
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
