2. Search Result
Search Result
Results for "

antifertility

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

1

Peptides

12

Natural
Products

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1192
    Estradiol benzoate
    Maximum Cited Publications
    16 Publications Verification

    β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate

    		 Estrogen Receptor/ERR HBV Bcl-2 Family Neurological Disease
    Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .
    Estradiol benzoate
  • HY-32736
    Triptonide
    3 Publications Verification

    NSC 165677; PG 492

    		 Wnt β-catenin Apoptosis Autophagy Inflammation/Immunology Cancer
    Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .
    Triptonide
  • HY-N2181
    Acetylshikonin
    3 Publications Verification

    		 Cytochrome P450 Apoptosis Bacterial Autophagy Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Acetylshikonin is an oral active anti-cancer, anti-inflammatory, antioxidant, anti-fertility, antibacterial, and neuroprotective agent. Acetylshikonin is a inhibitor of acetylcholinase (AChE) (IC50=34.6 μM) and nonselective cytochrome P450. Acetylshikonin can induce Apoptosis and Autophagy in cancer cells. Acetylshikonin regulates blood glucose, liver fat metabolism, and renal fibrosis, and is used in the study of diabetes, diabetic nephropathy (DN), obesity, and nonalcoholic fatty liver disease (NAFLD) .
    Acetylshikonin
  • HY-N1581
    Quassin

    Nigakilactone D

    		 Parasite Infection Endocrinology
    Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity .
    Quassin
  • HY-N6939
    Pseudolaric Acid B
    2 Publications Verification

    		 HBV Fungal Apoptosis Autophagy Ferroptosis Interleukin Related HIF/HIF Prolyl-Hydroxylase Infection Cardiovascular Disease Inflammation/Immunology Cancer
    Pseudolaric Acid B is an orally active diterpene acid. Pseudolaric Acid B has anti-fungal, anti-fertility, anti-angiogenesis and anticancer activity, and can induce tumor cell apoptosis and autophagy. In addition, Pseudolaric Acid B can inhibit the secretion of hepatitis B virus (HBV) and has immunosuppressive effect, selectively inhibiting the proliferation of T lymphocytes and the production of IL-2 .
    Pseudolaric Acid B
  • HY-B1904
    Fluphenazine decanoate

    		Dopamine Receptor Neurological Disease
    Fluphenazine decanoate is a CNS-penetrant dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .
    Fluphenazine decanoate
  • HY-123035
    Gamendazole

    		HSP Akt EGFR Endocrinology
    Gamendazole, an indazole carboxylic acid (ICA), is an orally active, selective HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A) inhibitor. Gamendazole binds to the C-terminal nucleotide binding pocket of HSP90 and cause downregulation of clients AKT1 and ERBB2, but stabilizes the HSP90 heterocomplex. Gamendazole specifically inhibits the actin bundling function of EEF1A1, but does not bind to the nucleotide docking pocket nor inhibits the ribosome charging or protein translation functions of EEF1A1. Gamendazole, an antispermatogenic compound with antifertility effects, has the potential for reversible non-hormonal male contraceptive agent research .
    Gamendazole
  • HY-N4088
    Pseudolaric acid A-O-β-D-glucopyranoside

    		Fungal Infection Endocrinology
    Pseudolaric acid A-O-β-D-glucopyranoside, isolated from Cortex Pseudolaricis, demonstrates antifungal and antifertility activities .
    Pseudolaric acid A-O-β-D-glucopyranoside
  • HY-B1192R
    Estradiol benzoate (Standard)

    β-Estradiol 3-benzoate (Standard); 17β-Estradiol 3-benzoate (Standard)

    		 Reference Standards Estrogen Receptor/ERR HBV Bcl-2 Family Neurological Disease
    Estradiol benzoate (Standard) is the analytical standard of Estradiol benzoate. This product is intended for research and analytical applications. Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .
    Estradiol benzoate (Standard)
  • HY-B1904A
    Fluphenazine decanoate dihydrochloride

    		Dopamine Receptor Neurological Disease
    Fluphenazine decanoate dihydrochloride is a CNS-penetrant dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .
    Fluphenazine decanoate dihydrochloride
  • HY-136092
    Androsta-1,4,6-triene-3,17-dione

    		Cytochrome P450 Neurological Disease Endocrinology
    Androsta-1,4,6-triene-3,17-dione is a lipophilic and specific aromatase inhibitor with a Ki of 0.18 μM. Androsta-1,4,6-triene-3,17-dione inhibits estrogen biosynthesis and shows antifertility effects. Androsta-1,4,6-triene-3,17-dione induces impairment of spatial memory .
    Androsta-1,4,6-triene-3,17-dione
  • HY-32736R
    Triptonide (Standard)

    NSC 165677 (Standard); PG 492 (Standard)

    		 Reference Standards Wnt β-catenin Apoptosis Autophagy Inflammation/Immunology Cancer
    Triptonide (Standard) is the analytical standard of Triptonide. This product is intended for research and analytical applications. Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .
    Triptonide (Standard)
  • HY-129638
    L-10503

    		Prostaglandin Receptor Endocrinology
    L-10503 is a non-hormonal non-prostaglandin antifertility compound .
    L-10503
  • HY-131729
    16-Phenoxy tetranor Prostaglandin A2

    		Drug Metabolite Cardiovascular Disease
    16-Phenoxy tetranor Prostaglandin A2 is a metabolite of uprostone and an analog of the antifertility hormone PGF2α .
    16-Phenoxy tetranor Prostaglandin A2
  • HY-118950
    J 628

    		Estrogen Receptor/ERR Endocrinology
    J 628 is an estrogen derivative used to study antifertility effects after sexual intercourse in mice, rats, and rabbits .
    J 628
  • HY-P2357
    MI-1544

    		GnRH Receptor Metabolic Disease
    MI-1544 is a powerful GnRH antagonist. MI-1544 induces inhibitory effects on the pituitary LH release and on gonads. MI-1544 can be used for the research of antifertility effect .
    MI-1544
  • HY-106299
    Lilopristone

    ZK98734

    		 Progesterone Receptor Metabolic Disease
    Lilopristone (ZK98734) is a progesterone antagonist with a potential to induce menstruation, inhibit nidation, and terminate pregnancy. Lilopristone blocks progesterone action at the endometrium as well as decreases progesterone bioavailability, and can be utilized in antifertility research .
    Lilopristone
  • HY-N1581R
    Quassin (Standard)

    Nigakilactone D (Standard)

    		 Reference Standards Parasite Infection Endocrinology
    Quassin (Standard) is the analytical standard of Quassin. This product is intended for research and analytical applications. Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity .
    Quassin (Standard)
  • HY-126476
    Justicisaponin I

    		Others Others
    Justicisaponin I can be used as an anti-fertility agent. Justicisaponin I stabilizes the acrosome membrane of sperm, and inhibits the release of acid hydrolase and sperm proteins .
    Justicisaponin I
  • HY-N4088R
    Pseudolaric acid A-O-β-D-glucopyranoside (Standard)

    		Reference Standards Fungal Infection Endocrinology
    Pseudolaric acid A-O-β-D-glucopyranoside (Standard) is the analytical standard of Pseudolaric acid A-O-β-D-glucopyranoside. This product is intended for research and analytical applications. Pseudolaric acid A-O-β-D-glucopyranoside, isolated from Cortex Pseudolaricis, demonstrates antifungal and antifertility activities .
    Pseudolaric acid A-O-β-D-glucopyranoside (Standard)
  • HY-N6939R
    Pseudolaric Acid B (Standard)

    		Reference Standards HBV Fungal Apoptosis Autophagy Ferroptosis HIF/HIF Prolyl-Hydroxylase Interleukin Related Infection Cardiovascular Disease Inflammation/Immunology Cancer
    Pseudolaric Acid B (Standard) is the analytical standard of Pseudolaric Acid B. This product is intended for research and analytical applications. Pseudolaric Acid B is an orally active diterpene acid. Pseudolaric Acid B has anti-fungal, anti-fertility, anti-angiogenesis and anticancer activity, and can induce tumor cell apoptosis and autophagy. In addition, Pseudolaric Acid B can inhibit the secretion of hepatitis B virus (HBV) and has immunosuppressive effect, selectively inhibiting the proliferation of T lymphocytes and the production of IL-2 .
    Pseudolaric Acid B (Standard)
  • HY-137355
    15(S)-15-methyl Prostaglandin D2

    15(S)-15-Methyl PGD2

    		 Prostaglandin Receptor Cardiovascular Disease Metabolic Disease
    15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2).
    15(S)-15-methyl Prostaglandin D2
  • HY-B1904R
    Fluphenazine decanoate (Standard)

    		Reference Standards Dopamine Receptor Neurological Disease
    Fluphenazine decanoate (Standard) is the analytical standard of Fluphenazine decanoate. This product is intended for research and analytical applications. Fluphenazine decanoate is a dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .
    Fluphenazine decanoate (Standard)
  • HY-105714
    Etoprine

    		Dihydrofolate reductase (DHFR) Endocrinology
    Etoprine is a potent orally active dihydrofolate reductase (DHFR) inhibitor. Etoprine competitively inhibits testicular DHFR to disrupt tetrahydrofolate and DNA synthesis in rapidly dividing cells. Etoprine acts as an antifertility agent in male mice and reduces fecundity in male rats .
    Etoprine
  • HY-N19880
    Oleanoglycotoxin A

    		Drug Derivative Infection
    Oleanoglycotoxin A is a saponin present in the berries of Phytolacca dodecandra, with antifertility and molluscicidal activities. Oleanoglycotoxin A prevents pregnancy, reduces the number of embryos, inhibits implantation, terminates established pregnancy, and kills Biomphalaria glabrata. Oleanoglycotoxin A can be used in studies related to schistosomiasis .
    Oleanoglycotoxin A
  • HY-182447
    Contragestazol

    DL111-IT

    		 CDK Apoptosis Endocrinology Cancer
    Contragestazol (DL111-IT) is a non-hormonal antifertility agent. Contragestazol reduces the expression of Cyclin D1 and CDK4, increases the expression of total retinoblastoma protein (pRb), and decreases the level of hyperphosphorylated pRb. Contragestazol induces G0/G1 phase cell cycle arrest. Contragestazol inhibits embryonic development by inducing luteal cell apoptosis and reducing intrauterine polyamine levels. Contragestazol exhibits antitumor activity against prostate cancer, S180 tumor and H22 tumor. Contragestazol shows extremely potent activity in terminating early pregnancy in animals .
    Contragestazol
  • HY-106074
    Mexiprostil

    MDL 646

    		 Drug Derivative Inflammation/Immunology
    Mexiprostil (MDL 646) is an orally active gastric protectant, being a synthetic analogue of Prostaglandin E1 (HY-B0131). Mexiprostil exhibits significant inhibition of gastric acid secretion caused by Histamine (HY-B1204) and Bethanechol (HY-B0406) in rats, dogs, and cats. Mexiprostil can also inhibit the increase in gastric acid secretion caused by Pentagastrin (HY-A0261) in cats, while it does not have this effect in dogs and rats. Mexiprostil does not cause pregnancy termination. Mexiprostil can be used for research on gastric ulcers .
    Mexiprostil

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: