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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
apolipoprotein E
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "apolipoprotein E" in MCE Product Catalog:
29
29 Publications Verification
Target:
Research Areas:
BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .
29
29 Publications Verification
Target:
Research Areas:
BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .
5
5 Cited Publications
Cat. No.: HY-P2136
CAS No.: 878009-24-6
Target:
Research Areas:
4
4 Cited Publications
Synonyms: DGLA; all-cis-8,11,14-Eicosatrienoic acid
Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-A0143A
CAS No.: 65881-87-0
Synonyms: DGLA sodium; all-cis-8,11,14-Eicosatrienoic acid sodium
Category:
Target:
3
3 Cited Publications
Cat. No.: HY-P702520
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
2
2 Cited Publications
Cat. No.: HY-P1050
CAS No.: 514200-66-9
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Research Areas:
COG 133 is a fragment of Apolipoprotein E (APOE) peptide. COG 133 competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 is also a nAChR antagonist with an IC50 of 445 nM .
2
2 Cited Publications
Cat. No.: HY-P1050A
CAS No.: 2828432-37-5
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P7531
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: APOE; apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); ApoE4; apolipoprotein E Isoform 4; Apo-E; apolipoprotein E Isoform 5; LPG; apolipoprotein E Isoform 2; apolipoprotein E; LDLCQ5
1
1 Cited Publications
Cat. No.: HY-P7532
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: APOE; apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); ApoE4; apolipoprotein E Isoform 4; Apo-E; apolipoprotein E Isoform 5; LPG; apolipoprotein E Isoform 2; apolipoprotein E; LDLCQ5
1
1 Cited Publications
Cat. No.: HY-P701096
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: APOE; apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); ApoE4; apolipoprotein E Isoform 4; Apo-E; apolipoprotein E Isoform 5; LPG; apolipoprotein E Isoform 2; apolipoprotein E; LDLCQ5
1
1 Cited Publications
Cat. No.: HY-P704765
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
1
1 Cited Publications
Cat. No.: HY-P704766
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
1
1 Cited Publications
Cat. No.: HY-P704767
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
Target:
Research Areas:
PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that could rescue impairments of mitochondrial motility and neurite outgrowth.
Synonyms: (E/Z)-Moschamine
Category:
Cardiovascular Disease Alkaloids Carthamus tinctorius L. Phenols Polyphenols Plants Compositae Disease Research Fields Indole Alkaloids
Target:
Cat. No.: HY-P2136F
Target:
Research Areas:
Cat. No.: HY-A0143S
CAS No.: 81540-86-5
Synonyms: DGLA-d6; all-cis-8,11,14-Eicosatrienoic acid-d6
Cat. No.: HY-176303S
Cat. No.: HY-169080
CAS No.: 2839627-76-6
Target:
Research Areas:
ABCA1 inducer 1 is a nonlipogenic ABCA1 inducer. ABCA1 inducer 1 increases ABCA1 expression, enhances apolipoprotein (APOE) lipidation and reverses multiple Alzheimer’s disease (AD) phenotypes, without increasing triglycerides in E3/4FAD mice that express human APOE 3/4 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
