81540-86-5
Chemical Structure
Dihomo-γ-linolenic acid-d6
Synonym(s): DGLA-d6; all-cis-8,11,14-Eicosatrienoic acid-d6
- CAS No.: 81540-86-5
- Formula:C20H28D6O2
- Molecular Weight:312.52
IUPAC Name: (8Z,11Z,14Z)-icosa-8,11,14-trienoic-8,9,11,12,14,15-d6 acid
InChIKey: HOBAELRKJCKHQD-JALKMEHMSA-N
SMILES: CCCCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCCCC(O)=O
Biological Activity:
Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].
The product specifications provided below refer solely to the active content of Dihomo-γ-linolenic acid-d6.
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Dihomo-γ-linolenic acid-d6 | 99.0% | Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system. The product specifications provided below refer solely to the active content of Dihomo-γ-linolenic acid-d6. |
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Dihomo-γ-linolenic acid | 99.77% | Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system. The product specifications provided below refer solely to the active content of Dihomo-γ-linolenic acid. |
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Similarity Score 0.97
HY-1675579(Z),12(Z),15(Z)-Heneicosatrienoic acid -
Similarity Score 0.97
HY-N162157(Z),10(Z),13(Z)-Nonadecatrienoic acid -
Similarity Score 0.97
HY-108398ASMead acid-d6 -
Similarity Score 0.97
HY-108398AMead acid -
Similarity Score 0.95
HY-N16217cis-10,13,16-Docosatrienoic acid -
Similarity Score 0.95
HY-N7140RGamma-Linolenic acid (Standard) -
Similarity Score 0.93
HY-W013215Adrenic acid -
Similarity Score 0.92
HY-1800469(Z),12(E)-Octadecadienoic acid -
Similarity Score 0.92
HY-N0729S2Linoleic acid-13C18 -
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Wang X, et al. Multiple roles of dihomo-γ-linolenic acid against proliferation diseases. Lipids Health Dis. 2012 Feb 14;11:25. [Content Brief]
- [3]. Gallagher H, et al. Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2538-2550. [Content Brief]
