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Dihomo-γ-linolenic acid sodium

(Synonyms: DGLA sodium; all-cis-8,11,14-Eicosatrienoic acid sodium)
4 Cited Publications
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Based on 4 publication(s) in Google Scholar

Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system.

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  • Purity: 99.9%
  • CAS No.: 65881-87-0
  • Formula: C20H33NaO2
  • Molecular Weight:328.46
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Dihomo-γ-linolenic acid sodium Chemical Structure
    Dihomo-γ-linolenic acid sodium Chemical Structure
  • Experimental Validation Results for Dihomo-γ-linolenic acid sodium
  • Experimental Validation Results for Dihomo-γ-linolenic acid sodium
  • Experimental Validation Results for Dihomo-γ-linolenic acid sodium
CAS No.: 65881-87-0
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  • Cell Proliferation/Viability Assay
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  • Dihomo-γ-linolenic acid sodium Chemical Structure
    Dihomo-γ-linolenic acid sodium Chemical Structure
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    Dihomo-γ-linolenic acid sodium purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2025 Jun 23. [Abstract]

    Customer Validation
     Cell viability analysis of SK-HEP-1 cells after treatment with 1 μM (20)S-APPT alone or simultaneously with DGLA (Dihomo-γ-linolenic acid; 50 μM; 72 h + 2 h for fixed). DGLA did not exhibit significant cytotoxicity.

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    Dihomo-γ-linolenic acid sodium purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Aug 8;15(1):6742. [Abstract]

    Customer Validation
     Quantification of murine N2A neuron viability after treatment with DGLA (Dihomo-γ-linolenic acid; 20-200 μg/mL; 24 h). DGLA alone did not induce neuronal cell death.

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    Dihomo-γ-linolenic acid sodium purchased from MedChemExpress. Usage Cited in: Cell Rep. 2022 Sep 20;40(12):111381. [Abstract]

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     Fecundity ratios of Δnhr-114 Caenorhabditis elegans continuously exposed to dietary DGLA (Dihomo-γ-linolenic acid; 2.5 mM) from the L1 stage to Day 2 adulthood. Dietary DGLA significantly reduced fecundity in Δnhr-114 animals.

  • Dihomo-γ-linolenic acid sodium