1783-84-2
1783-84-2
Chemical Structure
Dihomo-γ-linolenic acid
Synonym(s): DGLA; all-cis-8,11,14-Eicosatrienoic acid
- CAS No.: 1783-84-2
- Formula:C20H34O2
- Molecular Weight:306.48
IUPAC Name: (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid
InChIKey: HOBAELRKJCKHQD-QNEBEIHSSA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(O)=O
Biological Activity: Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dihomo-γ-linolenic acid | 99.77% | Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system. | ||||||||||||||||||||
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Dihomo-γ-linolenic acid-d6 | 99.0% | Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system. | ||||||||||||||||||||
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References
- [1]. Wang X, et al. Multiple roles of dihomo-γ-linolenic acid against proliferation diseases. Lipids Health Dis. 2012 Feb 14;11:25. [Content Brief]
- [2]. Gallagher H, et al. Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2538-2550. [Content Brief]
- [3]. Yang X, et al. Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA. Redox Biol. 2019 Jan;20:236-246. [Content Brief]
