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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
benzenesulfonamide derivative
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "benzenesulfonamide derivative" in MCE Product Catalog:
Cat. No.: HY-149269
CAS No.: 1160498-08-7
Target:
Research Areas:
COX-2-IN-30 is a benzenesulfonamide derivative, as well as an orally active and dual inhibitor of COX (IC50=49 nM for COX-2, 10.4 μM for COX-1) and 5-LOX (IC50=2.4 μM). COX-2-IN-30 also inhibits transmembrane hCA IX and hCA XII isoform with nanomolar calss Ki values. COX-2-IN-30 exhibits analgesic, anti-inflammatory, and ulcerogenic activities, and does not show acute gastric effect .
Cat. No.: HY-W394717
CAS No.: 1186532-61-5
Synonyms: PGN 1531
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BGC-20-1531 (PGN 1531), a benzenesulfonamide derivative, is a selective EP4 antagonist. BGC-20-1531 binds to PGE2 enhancing the ATPase activity, which are coupled to Gs proteins and thus activate adenylate cyclase generating cAMP and activating PKA. BGC-20-1531 is promising for research of liver disorders .
Cat. No.: HY-154794
CAS No.: 161805-15-8
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Research Areas:
Antiviral agent 29 (one of the Example I), a 2-mercapto-N-(5-amino-1,2,4-triazol-3-yl) benzenesulfonamide derivative, is an antiviral agent exhibiting anti-HIV, antitumor and antiarrhythmic activities .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
