336 Results for "

bi-functional

" in MedChemExpress (MCE) Product Catalog:
Products (336)

336 Results for "bi-functional" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-W019543
CAS No.: 68528-80-3
Research Areas:  

Cancer

Disuccinimidyl suberate Crosslinker is an amine-reactive bifunctional protein crosslinker. Disuccinimidyl suberate Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
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8
8 Cited Publications
Cat. No.: HY-111519
CAS No.: 2170695-14-2
Purity:  99.89%
Research Areas:  

Cancer

dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC, consists of ligands for von Hippel-Lindau and TRIM24.
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6
6 Cited Publications
Cat. No.: HY-129460
CAS No.: 866404-31-1
Purity:  99.15%
Research Areas:  

Neurological Disease

XJB-5-131 is a mitochondria-targeted ROS and electron scavenger . XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria . XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) .
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6
6 Cited Publications
Cat. No.: HY-138642
CAS No.: 2229711-68-4
Purity:  99.60%
Synonyms: ARV-471
Research Areas:  

Cancer

Vepdegestrant (ARV-471) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration (DC50) of about 2 nM .
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5
5 Cited Publications
Cat. No.: HY-D0975
CAS No.: 92921-24-9
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
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4
4 Cited Publications
Cat. No.: HY-13593
CAS No.: 305-03-3
Purity:  98.76%
Synonyms: CB-1348; WR-139013
Research Areas:  

Neurological Disease Cancer

Chlorambucil (CB-1348), an orally active antineoplastic agent, is a CNS-penetrant bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .
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3
3 Cited Publications
Cat. No.: HY-16503
CAS No.: 299-75-2
Synonyms: NSC 39069; Treosulphan
Research Areas:  

Cancer

Treosulfan (NSC 39069) is a bifunctional alkylating agent with activity in ovarian cancer and other solid tumor types.
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1
1 Cited Publications
Cat. No.: HY-114377
CAS No.: 127985-74-4
Purity:  99.78%
Research Areas:  

Cancer

p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor .
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1
1 Cited Publications
Cat. No.: HY-W123005
CAS No.: 58537-94-3
Research Areas:  

Others

Dimethyl pimelimidate dihydrochloride is a bifunctional imidoester protein-protein crosslinker used in chromatin immunoprecipitation (ChIP) assays .
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1
1 Cited Publications
Cat. No.: HY-156035
CAS No.: 102650-30-6
Purity:  96.05%
Research Areas:  

Inflammation/Immunology

Bz-DTPA is a bifunctional chelator. Bz-DTPA can be used for preparing immunoconjugate of monoclonal antibody 2G3 labeled with indium-111 .
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1
1 Cited Publications
Cat. No.: HY-134797
CAS No.: 1222468-90-7
Purity:  ≥98.0%
Research Areas:  

Cancer

P-SCN-Bn-deferoxamine is a bifunctional chelating agent that can link radioactive metal nuclides (such as Zr-89) and biological targeting molecules (such as antibodies). P-SCN-Bn-deferoxamine can be used for the research of immune PET imaging .
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Cat. No.: HY-P99944
CAS No.: 2891860-17-4
Synonyms: Retlirafusp alfa

Research Areas:  

Cancer

SHR-1701 (Retlirafusp alfa) is a bifunctional fusion protein targeting PD-L1 and TGF-β for cancer research .
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Cat. No.: HY-W539916
CAS No.: 1227407-76-2
Azido-mono-amide-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Azido-mono-amide-DOTA can be used for conjugation of peptides and radionuclides.
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Cat. No.: HY-113335
CAS No.: 547-98-8
Purity:  99.48%
Synonyms: Coprocholic acid
Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease .
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Cat. No.: HY-D0967
CAS No.: 146368-15-2
Cy5-bifunctional dye is a bifunctional dye used for covalent labeling of primary amines on proteins or oligonucleotides (Ex/Em = 649 nm/670 nm). Cy5-bifunctional dye can label recombinant annexin-V to assess phosphatidylserine exposure on the cell surface via flow cytometry. Cy5-bifunctional dye can label anti-human IgG (H + L) secondary antibodies. Cy5-bifunctional dye is applicable to studies of glanders and melioidosis .
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Cat. No.: HY-168941A
HS-PEG3500-COOH is a bi-functional PEG derivative. HS-PEG3500-COOH is used to synthesize PEG hydrogels .
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Cat. No.: HY-W749603
CAS No.: 479081-06-6
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.
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Cat. No.: HY-W102590
CAS No.: 91987-74-5
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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Cat. No.: HY-W678394
CAS No.: 865470-67-3
DOTA-Thiolis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-Thiol can be used for conjugation of peptides and radionuclides.
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Cat. No.: HY-48876
CAS No.: 181065-46-3
p-NH2-Bn-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. p-NH2-Bn-DOTA can be used for conjugation of peptides and radionuclides.
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