Bz-DTPA
Based on 1 publication(s) in Google Scholar
Bz‑DTPA is a bifunctional chelator that can conjugate indium radionuclides to targeting proteins for tumor-targeted tracing. Bz‑DTPA is mainly used in studies related to radioactive targeting molecules.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 96.18%
- CAS. Nr.: 102650-30-6
- Formel: C22H28N4O10S
- Molecular Weight:540.54
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Bz-DTPA
More
Biologische Aktivität
Beschreibung
In Vitro
Bz-DTPA, as part of the [111In]Bz-DTPA-hEGF conjugate, exhibits a plasma stability profile with transchelation of 111In to blood serum proteins occurring at 5.3% per day[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Bz‑DOTA‑derived 111In‑Bz‑DOTA‑ABD‑(ZHER2:342)2 (total protein 20 μg, containing 30 kBq; subcutaneous injection) exhibits specific and time‑dependent uptake in LS174T colorectal carcinoma xenografts of Balb/c nu/nu mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 102650-30-6
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Appearance Solid
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Molecular Weight 540.54
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Formel C22H28N4O10S
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Color White to off-white
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SMILES
OC(CN(CC(O)=O)[C@H](CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O)CC1=CC=C(C=C1)N=C=S)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 25 mg/mL (46.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 5 mg/mL (9.25 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (286 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 1.8500 mL | 9.2500 mL | 18.5000 mL | 46.2500 mL |
| 5 mM | 0.3700 mL | 1.8500 mL | 3.7000 mL | 9.2500 mL | |
| DMSO | 10 mM | 0.1850 mL | 0.9250 mL | 1.8500 mL | 4.6250 mL |
| 15 mM | 0.1233 mL | 0.6167 mL | 1.2333 mL | 3.0833 mL | |
| 20 mM | 0.0925 mL | 0.4625 mL | 0.9250 mL | 2.3125 mL | |
| 25 mM | 0.0740 mL | 0.3700 mL | 0.7400 mL | 1.8500 mL | |
| 30 mM | 0.0617 mL | 0.3083 mL | 0.6167 mL | 1.5417 mL | |
| 40 mM | 0.0463 mL | 0.2313 mL | 0.4625 mL | 1.1563 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Bz-DTPA Related Classifications
HY-156035 Related Classifications
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