1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. DSS Crosslinker

DSS Crosslinker 

Cat. No.: HY-W019543 Purity: >98.0%
Handling Instructions

DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

DSS Crosslinker Chemical Structure

DSS Crosslinker Chemical Structure

CAS No. : 68528-80-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 61 In-stock
Estimated Time of Arrival: December 31
100 mg USD 55 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Non-cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

368.34

Formula

C₁₆H₂₀N₂O₈

CAS No.

68528-80-3

SMILES

O=C(ON1C(CCC1=O)=O)CCCCCCC(ON2C(CCC2=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (339.36 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7149 mL 13.5744 mL 27.1488 mL
5 mM 0.5430 mL 2.7149 mL 5.4298 mL
10 mM 0.2715 mL 1.3574 mL 2.7149 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

DSS CrosslinkerADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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DSS Crosslinker
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HY-W019543
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