8 Results for "

cancer imaging components

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "cancer imaging components" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P5290
CAS No.: 2213408-17-2
Research Areas:  

Cancer

HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research . HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
loading...
    loading...
Cat. No.: HY-P5292A
CAS No.: 2375849-11-7
Research Areas:  

Cancer

HYNIC-iPSMA TFA is a PSMA-targeted ligand for tumor molecular imaging, with a Ki value of 3.11 nM. HYNIC-iPSMA TFA consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC serves as a chelating moiety to link radionuclides to the targeting molecule; iPSMA is a specific inhibitor that targets Prostate-Specific Membrane Antigen (PSMA). 68Ga-labeled iPSMA is used for prostate cancer detection via PET imaging, while the further developed 99mTc-EDDA/HYNIC-iPSMA TFA exhibits excellent specificity and sensitivity. HYNIC-iPSMA TFA can be used for the synthesis and research of radionuclide-conjugated drugs (RDC) .
loading...
    loading...
Cat. No.: HY-P5292
CAS No.: 2192215-74-8
Research Areas:  

Cancer

HYNIC-iPSMA is a PSMA-targeted ligand for tumor molecular imaging, with a Ki value of 3.11 nM. HYNIC-iPSMA consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC acts as a chelating moiety to link radionuclides to the targeting molecule; iPSMA is a specific inhibitor that targets Prostate-Specific Membrane Antigen (PSMA). 68Ga-labeled iPSMA is used for prostate cancer detection via PET imaging, while the further developed 99mTc-EDDA/HYNIC-iPSMA TFA exhibits excellent specificity and sensitivity. HYNIC-iPSMA can be used for the synthesis and research of radionuclide-conjugated drugs (RDC) .
loading...
    loading...
Cat. No.: HY-184962
CAS No.: 2415493-70-6
Target:  

GLUT

Research Areas:  

Cancer

Fluorodeoxyglucopyranose is a GLUT1 transporter substrate with facilitated bidirectional plasma membrane transport dependent on substrate gradients and independent of membrane potential. Fluorodeoxyglucopyranose undergoes conjugation to neuropharmaceutical agents and cancer imaging components. Fluorodeoxyglucopyranose can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-P11590
Target:  

EGFR

Research Areas:  

Cancer

WGYRGFYC (WC8) is a selective HER2-targeting peptide that binds specifically to HER2 by mimicking the antigen-binding site of trastuzumab. The DOTA precursor of WGYRGFYC has a KD of 61.20 nM for HER2. WGYRGFYC enables specific and highly sensitive detection of HER2 expression in HER2-positive breast cancer cells and tumor tissues, and monitors the dynamic downregulation of HER2 expression. WGYRGFYC rapidly distributes to target tissues and is efficiently cleared from non-target tissues via the kidneys, generating an ideal tumor-to-background ratio in imaging; it is a component of the PET radiotracer Ga-DOTA-WC8. WGYRGFYC exhibits no significant cytotoxicity in breast cancer cells, and can be used for non-invasive imaging diagnosis and therapeutic efficacy evaluation of HER2-positive breast cancer .
loading...
    loading...
Cat. No.: HY-P992449
Synonyms: PRLR ADC antibody

Target:  

ADC Antibodies

Research Areas:  

Cancer

REGN2878 (PRLR ADC antibody) is a monoclonal antibody targeting the prolactin receptor (PRLR) and can block prolactin‑mediated activation of PRLR. REGN2878 exhibits an equilibrium dissociation constant (KD) of 1.05 nM and an IC50 of 0.344 nM for human PRLR. REGN2878 can be rapidly internalized and degraded in lysosomes by PRLR‑positive tumor cells, showing antigen‑specific binding and targeted enrichment properties. REGN2878 derivatives can be used as an immunoPET agent for antigen‑specific imaging of PRLR‑related tumors, and can also serve as a component of ADCs to exert anti‑tumor activity in breast cancer xenograft models. REGN2878 can be used in the research of breast cancer and prostate cancer. Isotype Comparison HY-P99001 .
loading...
    loading...
Cat. No.: HY-W585442
CAS No.: 105528-25-4
5,9,14,18,23,27,32,36-Octabutoxy-2,3-naphthalocyanine is a photosensitive material with excellent light absorption and electron conduction activity. 5,9,14,18,23,27,32,36-Octabutoxy-2,3-naphthalocyanine is widely used in optoelectronic devices and is considered to be an effective photocatalyst. 5,9,14,18,23,27,32,36-Octabutoxy-2,3-naphthalocyanine can be used to improve the performance of solar cells and increase the photoelectric conversion efficiency. 5,9,14,18,23,27,32,36-Octabutoxy-2,3-naphthalocyanine also has potential anti-tumor activity and can inhibit the proliferation of certain cancer cells. 5,9,14,18,23,27,32,36-Octabutoxy-2,3-naphthalocyanine exhibits excellent fluorescence properties in medical imaging, which helps to improve the clarity and accuracy of imaging. 5,9,14,18,23,27,32,36-Octabutoxy-2,3-naphthalocyanine is studied as a component of a novel compound delivery system to improve the targeting and release effect of the compound.
loading...
    loading...
Cat. No.: HY-L105S
853 compounds

Peptides, composed of amino acids, serve as crucial building blocks for proteins and have gained significant attention in drug development over the past decade. The advancements in production, modification, and analytical technologies have led to a surge in the potential applications of peptides in medicine. Peptides offer a number of advantages over small molecule drugs, including: greater target specificity and efficacy, more predictable metabolic profiles, easier delivery to where they are needed in the body, and fewer side effects. Peptides are increasingly appearing in all branches of medicine as components of innovative drugs, imaging agents, diagnostic agents, and other complex drugs such as peptide-drug conjugates. To date, more than 80 peptide drugs have been approved to treat a variety of diseases, including microbial infections, obesity, anti-diabetes, and cancer, as well as to develop cell targeting platforms and improve cell penetration properties.

MCE designs a unique collection of 853 peptide compounds. HY-L105S is a peptide compound library that can be provided with solution form based on HY-L105, and can be applied to peptides-based drug development.