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Cat. No.: HY-184962

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Fluorodeoxyglucopyranose

Fluorodeoxyglucopyranose is a GLUT1 transporter substrate with facilitated bidirectional plasma membrane transport dependent on substrate gradients and independent of membrane potential. Fluorodeoxyglucopyranose undergoes conjugation to neuropharmaceutical agents and cancer imaging components. Fluorodeoxyglucopyranose can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 2415493-70-6
Formula: C₆H₁₁FO₅
Molecular Weight:182.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Fluorodeoxyglucopyranose Chemical Structure

CAS No.: 2415493-70-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

^[1]

GLUT1

All GLUT Isoforms :

Chemical Information

CAS No. 2415493-70-6
Molecular Weight 182.15
Formula C₆H₁₁FO₅
SMILES

OC[C@@H]1[C@H]([C@@H]([C@H](C(O1)O)F)O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Signal Pathway Related

Fluorescent plasma-membrane potential dye assay
Fluorescent plasma-membrane potential dye assays measure changes in cell membrane potential using voltage-sensitive dyes whose fluorescence changes when cells depolarize or hyperpolarize. Anionic bis-oxonol dyes such as DiBAC4(3) enter depolarized cells more readily and show increased fluorescence after intracellular binding, while hyperpolarization reduces dye accumulation and fluorescence. FMP/FLIPR membrane-potential dyes are used for faster, homogeneous microplate assays of ion-channel or receptor-mediated membrane-potential changes.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zerangue N, et al. GLUT1 transporters expressed in cancer cells. WO2005117931 A2. 2005 Dec 15.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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