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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
273 Results for "
chemical structure
" in MedChemExpress (MCE) Product Catalog:
Products (273)
273 Results for "chemical structure" in MCE Product Catalog:
11
11 Publications Verification
Cat. No.: HY-P1902
CAS No.: 115722-23-1
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11
11 Publications Verification
Cat. No.: HY-P1902A
CAS No.: 2918768-05-3
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5
5 Cited Publications
Synonyms: SGK3-PROTAC1
PROTAC SGK3 degrader-1 (SGK3-PROTAC1), a chemical probe, is a von Hippel-Lindau ligand-based SKG3 PROTAC composed of a PEG3-C4-OBn (HY-130620) alkyl linker, an SGK3 degrader (red structure), and a VHL ligand (HY-150803, blue structure). PROTAC SGK3 degrader-1 (0.3 μM) induced 50% endogenous SGK3 degradation within 2 hours, and 80% SGK3 degradation was observed at 8 hours, accompanied by loss of phosphorylation of NDRG1 (SGK3 substrate) .
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4 Cited Publications
Cat. No.: HY-N0772
CAS No.: 24699-16-9
2
2 Cited Publications
Cat. No.: HY-15917A
CAS No.: 16096-97-2
2
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1
1 Cited Publications
Cat. No.: HY-D1730
CAS No.: 1374019-99-4
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AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
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1 Cited Publications
Cat. No.: HY-D1730A
Synonyms: Ethyl docosahexaenoate
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Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects .
Cat. No.: HY-175238
CAS No.: 1309288-83-2
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KI-DX-014 is a DDX21 inhibitor with high RNA-binding inhibitory activity (IC50 of 3.31 μM). KI-DX-014 targets DDX21’s intrinsically disordered C-terminal domain, inhibits DDX21-structured RNA interaction, modulates DDX21’s RNA-dependent ATPase activity, and disrupts DDX21 biomolecular condensate formation. KI-DX-014 attenuates in vitro P-TEFb release from the 7SK snRNP complex, suppresses P-TEFb-dependent RNA polymerase II CTD phosphorylation, and induces developmental defects in zebrafish embryos. KI-DX-014 acts as a chemical probe for dissecting DDX21 functions in normal physiology and disease states. KI-DX-014 can be used for cancers and neurodegenerative disorders research .
Cat. No.: HY-W012848
CAS No.: 618-36-0
Synonyms: DL-α-Methylbenzylamine
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1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase (tyrosine kinase) inhibitor CLM3 (HY-164413) .
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Dicyclanil is an insect growth regulator compound with a similar chemical structure to cyromazine .
Cat. No.: HY-W784557
CAS No.: 171285-25-9
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O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography .
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3,4-Benzocoumarin is a kind of the expanded structure of coumarin derivatives.Coumarin is a chemical compound in the benzopyrone chemical class that can be found in many natural species. Coumarins possess variety of biological activities and unique photophysical properties . 3,4-Benzocoumarin, a AOH‐like compound , has the sensibility of the antibody with an IC50 of 919.2 ng/mL .
Cat. No.: HY-W141394
CAS No.: 85079-00-1
Synonyms: N-Benzoyl-2′-O-methyladenosine
Research Areas:
Bz-OMe-rA (N-Benzoyl-2′-O-methyladenosine) is a nucleoside analog with an N-benzoyl protecting group and a 2'-O-methyladenosine phosphoramidite unit. Bz-OMe-rA serves as a starting material for the chemical synthesis of the 5'-terminal cap structure of cytoplasmic polyhedrosis virus mRNA and also acts as a building block for solid-phase RNA oligonucleotide synthesis .
Synonyms: cis-10-Pentadecenoic acid
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10(Z)-Pentadecenoic acid is an unsaturated fatty acid. Unsaturated fatty acids are an important class of lipid molecules whose chemical structure contains one or more double bonds.
Cat. No.: HY-174968B
Synonyms: 4-Arm-PEG10000-Acrylate
Cat. No.: HY-W142618
CAS No.: 13265-84-4
Cat. No.: HY-W099600
CAS No.: 645-66-9
Synonyms: Bisdodecanoic anhydride
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
