85079-00-1
Chemical Structure
Bz-OMe-rA
Synonym(s): N-Benzoyl-2′-O-methyladenosine
- CAS No.: 85079-00-1
- Formula:C18H19N5O5
- Molecular Weight:385.37
IUPAC Name: N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
InChIKey: PHFHSPQCDRKMQJ-XWXWGSFUSA-N
SMILES: O[C@H]1[C@@H](OC)[C@H](N2C=NC3=C(N=CN=C32)NC(C4=CC=CC=C4)=O)O[C@@H]1CO
Biological Activity: Bz-OMe-rA (N-Benzoyl-2′-O-methyladenosine) is a nucleoside analog with an N-benzoyl protecting group and a 2'-O-methyladenosine phosphoramidite unit. Bz-OMe-rA serves as a starting material for the chemical synthesis of the 5'-terminal cap structure of cytoplasmic polyhedrosis virus mRNA and also acts as a building block for solid-phase RNA oligonucleotide synthesis[1][2].
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Bz-OMe-rA | 99.25% | Bz-OMe-rA (N-Benzoyl-2′-O-methyladenosine) is a nucleoside analog with an N-benzoyl protecting group and a 2'-O-methyladenosine phosphoramidite unit. Bz-OMe-rA serves as a starting material for the chemical synthesis of the 5'-terminal cap structure of cytoplasmic polyhedrosis virus mRNA and also acts as a building block for solid-phase RNA oligonucleotide synthesis. | ||||||||||||||||||||
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- [1]. Yamaguchi K, et al. Chemical synthesis of the 5'-terminal part bearing cap structure of messenger RNA of cytoplasmic polyhedrosis virus (CPV): m7G5'pppAmpG and m7G5'pppAmpGpU. Nucleic Acids Res. 1984 Mar 26;12(6):2939-54.
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[2]. Kadokura M, et al. Solid‑phase synthesis of a 5′‑terminal TMG‑capped trinucleotide block of U1 snRNA. Tetrahedron Letters, 2001, 42(50): 8853‑8856.
Keywords
