957-68-6
957-68-6
Chemical Structure
7-Aminocephalosporanic acid
Synonym(s): 7-ACA
- CAS No.: 957-68-6
- Formula:C10H12N2O5S
- Molecular Weight:272.28
IUPAC Name: (6R,7R)-3-(acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: HSHGZXNAXBPPDL-HZGVNTEJSA-N
SMILES: O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](N)C1=O)O
Biological Activity: 7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor[1][2].
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7-Aminocephalosporanic acid | 98.0% | 7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor. | ||||||||||||||||||||
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7-Aminocephalosporanic acid (Standard) | ≥98% | 7-Aminocephalosporanic acid (Standard) is the analytical standard of 7-Aminocephalosporanic acid. This product is intended for research and analytical applications. 7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor. | ||||||||||||||||||||
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References
- [1]. Ding JM, et al. Identification and Characterization of a New 7-Aminocephalosporanic Acid Deacetylase from Thermophilic Bacterium Alicyclobacillus tengchongensis. J Bacteriol. 2015 Nov 2;198(2):311-20. [Content Brief]
- [2]. Zhang W, et al. 7-aminocephalosporanic acid, a novel HSP90β inhibitor, attenuates HFD-induced hepatic steatosis. Biochem Biophys Res Commun. 2022 Sep 24;622:184-191. [Content Brief]
