Cephalosporin C zinc salt
Based on 1 publication(s) in Google Scholar
Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 μM. Cephalosporin C zinc salt also has moderate anti-orthopoxvirus activity.
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 59143-60-1
- Formula: C16H19N3O8SZn
- Molecular Weight:478.78
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Cephalosporin C zinc salt
MoreAll Antibiotic Isoforms
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Biological Activity
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β-lactam |
Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 ± 0.1 μM, 200-fold more potent than Na+ salt form of Cephalosporin C (ICC50CC-Na = 213 ± 30 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 59143-60-1
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Appearance Solid
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Molecular Weight 478.78
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Formula C16H19N3O8SZn
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Color White to off-white
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SMILES
CC(OCC1=C(C([O-])=O)N(C([C@H]2NC(CCC[C@@H](N)C([O-])=O)=O)=O)[C@]2([H])SC1)=O.[Zn+2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 5 mg/mL (10.44 mM; ultrasonic and adjust pH to 3 with 1M HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0886 mL | 10.4432 mL | 20.8864 mL | 52.2160 mL |
| 5 mM | 0.4177 mL | 2.0886 mL | 4.1773 mL | 10.4432 mL | |
| 10 mM | 0.2089 mL | 1.0443 mL | 2.0886 mL | 5.2216 mL |