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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
chrysin
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "chrysin" in MCE Product Catalog:
16
16 Cited Publications
Synonyms: 5,7-Dihydroxyflavone
Category:
Flavones Plants Oroxylum indicum (Linn.) Bentham ex Kurz Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Phenols Polyphenols Bignoniaceae Disease Research Fields Cancer
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1 Cited Publications
Referencia número: HY-N2376
No. CAS: 35775-49-6
Category:
Flavones Plants Oroxylum indicum (Linn.) Bentham ex Kurz Flavonoids Monophenols Labiatae Other Diseases Phenols Bignoniaceae Disease Research Fields Medicago truncatula Gaertn.
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Referencia número: HY-160250
No. CAS: 2097024-37-6
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Áreas de investigación:
UGT1A1-IN-1 is a UGT1A1 inhibitor and fluorescent probe (Ex=370 nm, Em=520 nm), with an IC50 of 1.33 μM and a Ki of 5.02 μM. UGT1A1-IN-1 is selectively glucuronidated by UGT1A1 at the bilirubin homologous binding site, and its PET effect is blocked along with this reaction, triggering fluorescence changes. UGT1A1-IN-1 can serve as a substitute for bilirubin to detect UGT1A1 activity and perform high-throughput screening of UGT1A1 modulators .
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Referencia número: HY-129131
No. CAS: 185145-33-9
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Referencia número: HY-125849
No. CAS: 88640-89-5
Synonyms: chrysin 7-O-β-gentiobioside
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Referencia número: HY-N2376R
No. CAS: 35775-49-6
Category:
Flavonoids Monophenols Flavones Labiatae Phenols Plants Bignoniaceae Oroxylum indicum (Linn.) Bentham ex Kurz Medicago truncatula Gaertn.
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Referencia número: HY-N13388
No. CAS: 27939-38-4
Synonyms: UGT1A6
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Referencia número: HY-N8639
No. CAS: 160880-89-7
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Referencia número: HY-167770
No. CAS: 863992-13-6
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Áreas de investigación:
Chrysin 7-sulfate is a conjugated metabolite of Chrysin (HY-14589). Chrysin 7-sulfate can strongly displace the Site I marker warfarin from human serum albumin. Chrysin 7-sulfate can effectively displace Ochratoxin A (OTA) (HY-N6788) from albumin both in vitro and in vivo .
Referencia número: HY-161757
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Áreas de investigación:
Anti-inflammatory agent 86 is a Chrysin (HY-14589) derivative with anti-inflammatory effects. Anti-inflammatory agent 86 inhibits monocyte adhesion to colon epithelium induced by TNF-α, with an IC50 of 4.71 μM. Anti-inflammatory agent 86 has the potential for the inflammatory bowel disease (IBD) research .
Referencia número: HY-172175
HYS-072 is an orally active derivative of chrysin (HY-14589) with antitumor activity. HYS-072 induces apoptosis and autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway and suppresses tumor growth in vivo in xenograft models by modulating autophagy-related pathways. HYS-072 can be used in the research of triple-negative breast cancer .
Referencia número: HY-N13552
No. CAS: 35775-46-3
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Referencia número: HY-144392
No. CAS: 84212-49-7
Áreas de investigación:
AChE/BuChE-IN-1 (Compound 1), a chrysin derivative, is a selective butyrylcholinesterase (BuChE) inhibitor with an IC50 of 0.48 μM. AChE/BuChE-IN-1 inhibits acetylcholinesterase (AChE) with an IC50 of 7.16 μM. AChE/BuChE-IN-1 shows strong scavenging ·OH activities with a IC50 of 0.1674 μM. AChE/BuChE-IN-1 inhibits reactive oxygen species (ROS), Aβ1-42 aggregation (self-, Cu2+-induced, AChE-induced). AChE/BuChE-IN-1 has high BBB permeability and bioavailability and low cell toxicity. AChE/BuChE-IN-1 has the potential for Alzheimer' disease (AD) research .
Referencia número: HY-N20679
No. CAS: 31025-53-3
Synonyms: chrysin 7-β--D-glucoside
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
