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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
craniofacial
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "craniofacial" in MCE Product Catalog:
8
Category:
Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Cancer Indole Alkaloids
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6
6 Cited Publications
Cat. No.: HY-18312
CAS No.: 1166393-85-6
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PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. PF-4618433 may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects and for targeted bone regeneration .
Cat. No.: HY-159642
CAS No.: 2800223-30-5
Synonyms: TYRA-300
Research Areas:
Dabogratinib (TYRA-300) is an orally active, selective FGFR3 inhibitor with an IC50 of 11 nM. Dabogratinib exhibits antitumor activity against urothelial carcinoma and solid tumors. Dabogratinib downregulates the FGFR3 and ERK1/2 signaling pathways, and induces tumor growth inhibition and regression in FGFR3-altered xenograft models. Dabogratinib promotes chondrocyte proliferation and differentiation, drives endochondral bone formation and overall body growth, partially restores long bone proportions, and improves craniofacial and spinal morphology. Dabogratinib can be used for the research of metastatic urothelial carcinoma, achondroplasia and hypochondroplasia .
Category:
Microorganisms Monophenols Coumarins Phenols Phenylpropanoids Disease Research Fields Cancer
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Cat. No.: HY-Y0332H
CAS No.: 13472-35-0
Synonyms: Sodium phosphate monobasic dihydrate, for molecular biology
Dipropyl phthalate is a plasticizer. Dipropyl phthalate induced activation of the FoxO signaling pathway, leading to abnormal proliferation of pharyngeal arch cartilage and promoting its apoptosis in a zebrafish model. Dipropyl phthalate also induced developmental defects in the craniofacial cartilage of zebrafish embryos in a zebrafish model .
Cat. No.: HY-159642G
CAS No.: 2800223-30-5
Synonyms: TYRA-300 (GMP)
Cat. No.: HY-174643
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Research Areas:
Human IL11RA mRNA encodes the human interleukin 11 receptor subunit alpha (IL11RA) protein, a member of the hematopoietic cytokine receptor family. IL11RA is essential for the normal development of craniofacial bones and teeth.
Cat. No.: HY-N6786S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
