Search Result

Results for "

dichloromethane extract

" in MedChemExpress (MCE) Product Catalog:

By Targets:	COX (1) Drug Derivative (1) Interleukin Related (1) Lipoxygenase (1)
By Research Areas:	Inflammation/Immunology (3) Metabolic Disease (1)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-133865

Diacetoxy-6-gingerdiol 1 Publications Verification	Interleukin Related	Metabolic Disease Inflammation/Immunology
Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .

HY-N3935

Gelomulide N	Others	Others
Gelomulide N is a compound that can be isolated from dichloromethane soluble extract of Gelonium aequoreum .

HY-N1827

3-epi-Maslinic acid	Others	Others
3-epi-Maslinic acid is an acidic pentacyclic triterpene isolated from Hexane and dichloromethane extracts of Platostoma africanum P. Beauv .

HY-N7324

Dehydroperilloxin	COX	Inflammation/Immunology
Dehydroperilloxin is a natural compound isolated from the dichloromethane extract of the stems of Perilla frutescens var. acuta. Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC₅₀ value of 30.4 μM .

HY-N19719

Bispyrayafoline	Drug Derivative	Inflammation/Immunology
Bispyrayafoline is a pyrrolidone and antioxidant with an IC₅₀ value of 13.85 μM against DPPH. Bispyrayafoline can be found in the leaves of Murraya koenigii (Linn.) Spreng. Bispyrayafoline's antioxidant activity is concentration-dependent but time-independent. Bispyrayafoline can be utilized in studies concerning oxidative damage .

HY-N16694

6,7-Dehydroferruginol	Lipoxygenase	Others
6,7-Dehydroferruginol is a diterpenoid compound that can be isolated from the dichloromethane extract of Juniperus communis wood. At a concentration of 100 μg/mL, 6,7-Dehydroferruginol showed no inhibitory activity against 12(S)-LOX and did not inhibit the production of 12(S)-HETE .

Diacetoxy-6-gingerdiol 1 Publications Verification	Zingiber officinale Roscoe Monophenols Classification of Application Fields Other Diseases Phenols Plants Disease Research Fields Source Classification Zingiberaceae	Interleukin Related
Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .

Gelomulide N	Triterpenes Terpenoids Yucca gloriosa L. Plants Source Classification Asparagaceae Juss.	Others
Gelomulide N is a compound that can be isolated from dichloromethane soluble extract of Gelonium aequoreum .

Dehydroperilloxin	Natural Products Labiatae Dicerothamnus rhinocerotis Plants Source Classification	COX
Dehydroperilloxin is a natural compound isolated from the dichloromethane extract of the stems of Perilla frutescens var. acuta. Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC₅₀ value of 30.4 μM .

Bispyrayafoline	Structural Classification Alkaloids Rutaceae Murraya koenigii (L.) Spreng Carbazole Alkaloids Plants Source Classification	Drug Derivative
Bispyrayafoline is a pyrrolidone and antioxidant with an IC₅₀ value of 13.85 μM against DPPH. Bispyrayafoline can be found in the leaves of Murraya koenigii (Linn.) Spreng. Bispyrayafoline's antioxidant activity is concentration-dependent but time-independent. Bispyrayafoline can be utilized in studies concerning oxidative damage .

6,7-Dehydroferruginol	Structural Classification Juniperus communis L. Cupressaceae Terpenoids Diterpenoids Plants Source Classification	Lipoxygenase
6,7-Dehydroferruginol is a diterpenoid compound that can be isolated from the dichloromethane extract of Juniperus communis wood. At a concentration of 100 μg/mL, 6,7-Dehydroferruginol showed no inhibitory activity against 12(S)-LOX and did not inhibit the production of 12(S)-HETE .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
Email *

	Sorry, but the email address you supplied was invalid.

dichloromethane extract

Inhibitors & Agonists

NaturalProducts

Natural
Products