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Cat. No.: HY-N19719

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Bispyrayafoline

Bispyrayafoline is a pyrrolidone and antioxidant with an IC₅₀ value of 13.85 μM against DPPH. Bispyrayafoline can be found in the leaves of Murraya koenigii (Linn.) Spreng. Bispyrayafoline's antioxidant activity is concentration-dependent but time-independent. Bispyrayafoline can be utilized in studies concerning oxidative damage.

For research use only. We do not sell to patients.

CAS No.: 1715114-37-6
Formula: C₄₆H₄₈N₂O₄
Molecular Weight:692.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Bispyrayafoline Chemical Structure

CAS No.: 1715114-37-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	20 μM Compound: 37	Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by WST-1 assay Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by WST-1 assay	[PMID: 34838335]

In Vitro

Bispyrayafoline's (Compound 11) (1-100 μM; 0.5-24 h) free radical scavenging activity increases with increasing concentration, but is independent of time (100 μM)^[2].

Bispyrayafoline (30 min) exhibits an IC₅₀ of 13.85 μM against DPPH^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1715114-37-6
Molecular Weight 692.88
Formula C₄₆H₄₈N₂O₄
SMILES

OC1=CC=C(C2=CC(C)=C(OC(C)(C=C3)CC/C=C(C)/C)C3=C2N4)C4=C1C5=C6C(C7=CC(C)=C(OC(C)(C=C8)CC/C=C(C)/C)C8=C7N6)=CC=C5O
Structure Classification
- Alkaloids
- Carbazole Alkaloids
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tan SP, et al. Isolation and cytotoxic investigation of new carbazole alkaloids from Murraya koenigii (Linn.) Spreng. Tetrahedron. 2015 Jun 10;71(23):3946-3953.

[2]. Tachibana Y, et al. Comparison of antioxidative properties of carbazole alkaloids from Murraya koenigii leaves. J Agric Food Chem. 2003 Oct 22;51(22):6461-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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