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dimeric IL-2 receptors

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Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-P991000
    Imneskibart

    AU-007; BD-8; BDG8

    		 Interleukin Related Cardiovascular Disease Inflammation/Immunology Cancer
    Imneskibart (AU-007) is a human monoclonal antibody that binds to the CD25-binding epitope of interleukin-2 (IL-2), blocking the binding of IL-2 to the trimeric IL-2 receptor while retaining the ability to bind to the dimeric IL-2 receptor. Imneskibart expands effector T cell and NK cell populations, reduces regulatory T cells, increases the effector T cell/regulatory T cell ratio, and alleviates vascular leakage. Imneskibart can be used in research related to melanoma and non-small cell lung cancer. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
    Imneskibart

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