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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
elongase
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "elongase" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-W010629
CAS No.: 79-07-2
2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase .
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ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor with IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-4 shows excellent selectivity over the other human ELOVL subtypes (ELOVL1, -2, -3, and -5) and mouse ELOVL3 .
Cat. No.: HY-160912
CAS No.: 1135000-36-0
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ELOVL6-IN-5 is an orally active and selective elongase enzyme of long-chain fatty acid family 6 (ELOVL6) inhibitor with IC50 values of 85 nM and 38 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-5 shows >60-fold selectivity over other ELOVL family enzymes (ELOVL1, 2, 3, 5) and no effect on other lipid synthesis enzymes like ACC1, ACC2. ELOVL6-IN-5 reduces hepatic fatty acid composition ratio of C18 to C16 in diet-induced obesity (DIO) and KKAy mice. ELOVL6 inhibition by ELOVL6-IN-5 does not improve insulin resistance. ELOVL6-IN-5 can be used for the research of metabolic disease .
Cat. No.: HY-B2013
CAS No.: 71283-80-2
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Fenoxaprop-P-ethyl is an acetyl-CoA carboxylase (ACC) inhibitor and post-emergence herbicide. Fenoxaprop-P-ethyl inhibits the conversion of acetyl-CoA to malonyl-CoA, reduces malonyl-CoA synthesis and disrupts fatty acid synthesis. Fenoxaprop-P-ethyl disrupts lipid homeostasis through cascaded inhibition of lipid metabolism, decreases total lipid content, downregulates fatty acid elongase genes and inhibits their activity. Fenoxaprop-P-ethyl disrupts fatty acid synthesis in rice seedlings and controls annual monocotyledonous weeds in wheat, durum wheat, rye, triticale and barley fields .
Cat. No.: HY-W010629R
CAS No.: 79-07-2
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2-Chloroacetamide (Standard) is the analytical standard of 2-Chloroacetamide. This product is intended for research and analytical applications. 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase .
Cat. No.: HY-W010629S
CAS No.: 122775-20-6
Cat. No.: HY-P81813A
Synonyms: ELOVL FA elongase 5; Fatty acid elongase 1; hELO1; Very long chain 3-ketoacyl-CoA synthase 5
Cat. No.: HY-P810996
Synonyms: FACE, LCE, ELOVL6, Very long chain fatty acid elongase 6, 3-keto acyl-CoA synthase ELOVL6, ELOVL fatty acid elongase 6, Elongation of very long chain fatty acids protein 6, Fatty acid elongase 2, Fatty acyl-CoA elongase, Long-chain fatty-acyl elongase, Very long chain 3-ketoacyl-CoA synthase 6, Very long chain 3-oxoacyl-CoA synthase 6, ELOVL FA elongase 6, hELO2
Cat. No.: HY-W332206
CAS No.: 125306-83-4
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Cafenstrole acts as a herbicide. Cafenstrole is a potent inhibitor of microsomal elongase enzyme involved in the biosynthesis of fatty acids with alkyl chains longer han C18 .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
