ELOVL5 Antibody (YA1558)(PBS only)

Cat. No.: HY-P81813A: Data Sheet User Guide for Antibodies
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ELOVL5 Antibody (YA1558) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ELOVL5.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명
References

제품 설명

ELOVL5 Antibody (YA1558) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ELOVL5.

Host

Rabbit

분자량

Predicted band size: 35 kDa;

Observed band size: 35 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q9NYP7

Gene ID

60481 [NCBI]

Immunogen

A synthetic peptide of human ELOVL5

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators (By similarity) (PubMed:10970790, PubMed:20937905). In conditions where the essential linoleic and alpha linoleic fatty acids are lacking it is also involved in the synthesis of Mead acid from oleic acid (By similarity)

Subcellular Localization：Endoplasmic reticulum membrane; Multi-pass membrane protein; Cell projection, dendrite

Expression：
Tissue_specificity:Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum

Isoforms & Post-Translational Modification：Q9NYP7 has 3 isomers: Q9NYP7-1: 35293 Da (predicted); Q9NYP7-2: 38403 Da (predicted); Q9NYP7-3: 9580 Da (predicted).

Subunit：Interacts with TECR

Research Field

Cardiovascular

Synonyms

ELOVL FA elongase 5; Fatty acid elongase 1; hELO1; Very long chain 3-ketoacyl-CoA synthase 5

각종 서류

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/u-937-cell.html [Content Brief]