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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
endogenous ceramide
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "endogenous ceramide" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-113679
CAS No.: 100403-19-8
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Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity .
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1 Cited Publications
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P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor wirh an IC50 of 0.5 μM. P053 acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle. Whole-body adiposity regulator .
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D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor. D-NMAPPD regulates NMDA receptor properties by enhancing endogenous production of ceramides. D-NMAPPD has anticancer effecs .
Synonyms: N-Behenoyl-D-erythro-sphingosine; C22-ceramide; Cer d18:1/22:0
Cat. No.: HY-N10634
CAS No.: 74365-77-8
Synonyms: C16 Glucosyl(β) ceramide (d18:1/16:0)
Cat. No.: HY-124177A
CAS No.: 123408-74-2
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C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research .
Cat. No.: HY-N15841
CAS No.: 67492-18-6
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Cat. No.: HY-D1574
CAS No.: 94885-04-8
Cat. No.: HY-176568
Research Areas:
LCL768 is a ceramide analog. LCL768 attenuates PARKIN succination to promote PARKIN activation and mitophagy. LCL768 induces CerS1-mediated endogenous C18-ceramide accumulation in mitochondria to mediate mitophagy, which is dependent on DRP1 activation via nitrosylation at C644. LCL768 alters mitochondrial metabolism, resulting in fumarate depletion and leading to tumor suppression. LCL768 improves sensorimotor defects in neurodegenerative diseases like ALS .
Cat. No.: HY-116017
CAS No.: 111122-57-7
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C10 ceramide is an endogenous, bioactive sphingolipid,
Cat. No.: HY-124177AS
Cat. No.: HY-128753S6
CAS No.: 288846-88-8
Cat. No.: HY-124134
CAS No.: 366487-89-0
Synonyms: LCL102
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AD-2646 (LCL102), a ceramide analog, can kill leukemic T cells (EC50: 40 μM). AD-2646 triggers the cleavage of caspase-8, -9 and -3, as well as the caspase substrate PARP. AD-2646 is a ceramidase inhibitor. AD-2646 induces an accumulation of endogenous ceramide owing to perturbed ceramide metabolism .
Cat. No.: HY-128753S7
Cat. No.: HY-128753R
CAS No.: 1114-34-7
Cat. No.: HY-128753S3
CAS No.: 70849-22-8
Cat. No.: HY-128753S4
CAS No.: 83379-39-9
Cat. No.: HY-128753S5
CAS No.: 139657-61-7
Cat. No.: HY-172668
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C22 Ceramide (d18:1(14Z)/22:0) is an endogenous bioactive sphingolipid. C22 Ceramide (d18:1(14Z)/22:0) has the effects of promoting cell cycle arrest and inducing apoptosis .
Cat. No.: HY-N10634S
CAS No.: 71924-12-4
Synonyms: N-ω-CD3-Hexadecaoyl-glucopsychosie; GluCe(d18:1/16:0-d3); Glucosylceamide-d3 (d18:1/16:0-d3)
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
