35922-06-6
35922-06-6
Chemical Structure
D-NMAPPD
Synonym(s): (1R,2R)-B13
- CAS No.: 35922-06-6
- Formula:C23H38N2O5
- Molecular Weight:422.56
IUPAC Name: N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)tetradecanamide
InChIKey: XUSDVLHKNBOGJY-FYYLOGMGSA-N
SMILES: OC[C@H]([C@@H](C1=CC=C(C=C1)[N+]([O-])=O)O)NC(CCCCCCCCCCCCC)=O
Biological Activity: D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor. D-NMAPPD regulates NMDA receptor properties by enhancing endogenous production of ceramides. D-NMAPPD has anticancer effecs[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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D-NMAPPD | 99.74% | D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor. D-NMAPPD regulates NMDA receptor properties by enhancing endogenous production of ceramides. D-NMAPPD has anticancer effecs. | ||||||||||||||||||||
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References
- [1]. Marie-Elaine Laurier-Laurin, et al.Blockade of lysosomal acid ceramidase induces GluN2B-dependent Tau phosphorylation in rat hippocampal slices. Neural Plast. 2014;2014:196812. [Content Brief]
- [2]. M Selzner, et al.Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. Cancer Res. 2001 Feb 1;61(3):1233-40. [Content Brief]
Keywords
