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D-erythro-MAPP (Synonyms: D-e-MAPP)

Cat. No.: HY-137422
Handling Instructions

D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC50 of 1-5 μM in vitro.

For research use only. We do not sell to patients.

D-erythro-MAPP Chemical Structure

D-erythro-MAPP Chemical Structure

CAS No. : 143492-38-0

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D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC50 of 1-5 μM in vitro[1].

In Vitro

D-erythro-MAPP (D-e-MAPP) reduces the viability of MCF-7 cells in a dose-dependent manner with IC50 value of 4.4 μM, and 15.6 μM, respectively[1].
D-erythro-MAPP (D-e-MAPP) induces G0/G1 arrest in cell cycle progression resulting in growth suppression[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Human breast cancer MCF-7 cells.
Concentration: 24 h.
Incubation Time: 3.13-100 μM.
Result: Inhibited cell viability.
Molecular Weight





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