15 Results for "

epidermal differentiation

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "epidermal differentiation" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-101180
CAS No.: 3102-57-6
Purity:  99.85%
Synonyms: Ceramide 2
C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis, inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss .
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Cat. No.: HY-W014983
CAS No.: 141-12-8
Neryl acetate is an essential oil component. Neryl acetate upregulates genes associated with epidermal differentiation, skin barrier formation and ceramide synthesis; it also increases filaggrin expression, total lipid and ceramide contents. Neryl acetate acts as the core driver mediating the skin barrier-forming and antibacterial effects of Helichrysum italicum essential oil .
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Cat. No.: HY-77278
CAS No.: 39932-44-0
Research Areas:  

Others

25-Hydroxytachysterol3 is the metabolite of Vitamin D3 (HY-15398). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor (VDR) and aryl hydrocarbon receptor (AhR), liver X receptor α/β (LXR α/β) and peroxisome proliferator-activated receptor γ (PPARγ), stimulates the expression of CYP24A1 .
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Cat. No.: HY-133027
CAS No.: 273203-62-6
Purity:  99.40%
Synonyms: Tetradecyl nicotinate
Research Areas:  

Cancer

Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
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Cat. No.: HY-117081
CAS No.: 457100-08-2
C30(ω-hydroxy) Ceramide (d18:1/30:0), a sphingolipid, is an epidermis-specifically vital component of the water barrier in mammalian skin. C30(ω-hydroxy) Ceramide (d18:1/30:0) is expressed in epidermal keratinocytes and male germ cells during their differentiation and maturation. C30(ω-hydroxy) Ceramide (d18:1/30:0) deficiency in the epiderm of Elovl4 deletion or mutation mice .
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Cat. No.: HY-P4184
CAS No.: 550-21-0
Synonyms: (Ser4,Ile8)-Oxytocin
Isotocin is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin exerts biological effects by binding to its homologous isotocin receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids .
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Cat. No.: HY-111378A
CAS No.: 2320347-54-2
Target:  

Casein Kinase

Research Areas:  

Others

Casein Kinase II Inhibitor IV Hydrochloride is a small-molecule inducer of epidermal keratinocyte differentiation.
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Cat. No.: HY-174535
Target:  

mRNA

Research Areas:  

Cancer

Human TGFA mRNA encodes the human transforming growth factor alpha (TGFA) protein. TGFA is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development.
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Cat. No.: HY-W014983R
CAS No.: 141-12-8
Neryl acetate (Standard) is the analytical standard of Neryl acetate. This product is intended for research and analytical applications. Neryl acetate is an essential oil component. Neryl acetate upregulates genes associated with epidermal differentiation, skin barrier formation and ceramide synthesis; it also increases filaggrin expression, total lipid and ceramide contents. Neryl acetate acts as the core driver mediating the skin barrier-forming and antibacterial effects of Helichrysum italicum essential oil .
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Cat. No.: HY-133027R
CAS No.: 273203-62-6
Synonyms: Tetradecyl nicotinate (Standard)
Research Areas:  

Cancer

Myristyl nicotinate (Standard) is the analytical standard of Myristyl nicotinate. This product is intended for research and analytical applications. Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
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Cat. No.: HY-P4184A
Synonyms: (Ser4,Ile8)-Oxytocin acetate
Isotocin acetate is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin acetate exerts biological effects by binding to its homologous Isotocin acetate receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin acetate promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin acetate regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids .
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Cat. No.: HY-E70831
Target:  

IKK

Research Areas:  

Cancer

IκB kinase α (IKKα), one of the two catalytic subunits of the IKK complex involved in NF-κB activation, also functions as a molecular switch that controls epidermal differentiation. IKKα Recombinant Human Active Protein Kinase is a recombinant IKKα protein that can be used to study IKKα-related functions .
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Cat. No.: HY-P992413

Target:  

Integrin

Research Areas:  

Inflammation/Immunology

MOR102 is a fully human IgG4 monoclonal antibody and an ICAM-1 inhibitor, lacking cross-reactivity with ICAM-2 and ICAM-3. MOR102 binds to the LFA-1 binding site within ICAM-1 domain 1, blocks ICAM-1/LFA-1 interaction, binds human keratinocytes with increased binding to interferon-γ-stimulated keratinocytes. MOR102 inhibits lymphocyte adhesion, reduces lymphocyte proliferation, prevents local T-cell activation, reduces inflammatory infiltrate, restores orthokeratotic differentiation, and reduces epidermal thickness. MOR102 can be used for the research of psoriasis .
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Cat. No.: HY-P77624
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD1A; epidermal Dendritic Cell Marker CD1a; Prev. CD1; Cluster Of differentiation 1 A; T-Cell Surface Glycoprotein CD1a; CD1A Protein; T-Cell Surface Antigen T6/Leu-6; FCB6; CD1A Antigen, A Polypeptide; HTA1; HTa1 Thymocyte Antigen; R4; CD1a Antigen; T6;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76208
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD1A; epidermal Dendritic Cell Marker CD1a; Prev. CD1; Cluster Of differentiation 1 A; T-Cell Surface Glycoprotein CD1a; CD1A Protein; T-Cell Surface Antigen T6/Leu-6; FCB6; CD1A Antigen, A Polypeptide; HTA1; HTa1 Thymocyte Antigen; R4; CD1a Antigen; T6;
Species:  
Rhesus Macaque
Source:  
HEK293
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