CD1A Protein, Human (HEK293, His)

The CD1A protein is a key antigen-presenting molecule that binds self and non-self lipid and glycolipid antigens and presents them to T cell receptors on natural killer T cells. CD1A, as a B2M (beta-2-microglobulin) heterodimer, plays a central role in immune surveillance and regulation. CD1A Protein, Human (HEK293, His) is the recombinant human-derived CD1A protein, expressed by HEK293 , with C-His labeled tag. The total length of CD1A Protein, Human (HEK293, His) is 282 a.a., with molecular weight of 48-53 kDa.

The CD1A protein stands as a pivotal antigen-presenting molecule with the unique capacity to bind both self and non-self lipid and glycolipid antigens, facilitating their presentation to T-cell receptors on natural killer T-cells. Operating as a heterodimer with B2M (beta-2-microglobulin), this protein plays a central role in immune surveillance and regulation. Its interaction with CD74 further underscores its significance in the intricate machinery of the immune system, highlighting its role in orchestrating T-cell responses to diverse antigens.

Human

HEK293

C-His

P06126 (D19-V300)

909  [NCBI]

48-53 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.