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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
esterase assays
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "esterase assays" in MCE Product Catalog:
1
1 Cited Publications
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Research Areas:
Calcein Blue AM is a cell staining agent. Calcein Blue AM serves as a substrate for intracellular esterases, which hydrolyze its acetoxymethyl (AM) ester group to convert the non-fluorescent reagent into fluorescent Calcein Blue. Calcein Blue AM passively penetrates the plasma membrane of both live and dead cells; it is converted into a polar fluorescent product and retained in the cytoplasm of live cells, whereas dead cells cannot retain the dye. Calcein Blue AM exhibits significant dye leakage, and its fluorescence intensity gradually decreases over time. Calcein Blue AM can be used for endpoint-based cell viability assays and short-term cell tracking experiments with a duration of no more than 4 hours.
Cat. No.: HY-W014449
CAS No.: 2635-84-9
Cat. No.: HY-D1678
CAS No.: 164256-07-9
Cat. No.: HY-W099563
CAS No.: 14617-86-8
4-Nitrophenyl octanoate (p-Nitrophenyl caprylate) is an aromatic ester compound which can be used as a substrate for pancreatic lipase.
4-Nitrophenyl octanoate contains an ester bond that can be hydrolyzed under the action of lipase, releasing p-nitrophenol as a yellow product.
4-Nitrophenyl octanoate can be used to assay the activities of lipases and esterases .
Cat. No.: HY-130431
CAS No.: 83792-61-4
Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.
Cat. No.: HY-187344
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Research Areas:
GLP-1R prodrug-1 is a GLP-1R agonist prodrug. GLP-1R prodrug-1 lacks direct GLP-1R agonistic activity. GLP-1R prodrug-1 is slowly converted into its active free acid metabolite GLP-1R agonist 45 (HY-187343) in plasma via esterase-mediated hydrolysis. GLP-1R prodrug-1 can be used in the research of type 2 diabetes and obesity .
Cat. No.: HY-D3431
CFSE-Tz is a fluorescent bioorthogonal probe constructed based on the IEDDA reaction, which is mainly used for visual tracing of amino acid uptake in living cells. The tetrazine group within the CFSE-Tz molecule quenches CFSE fluorescence via photoinduced electron transfer; after the probe specifically undergoes a bioorthogonal reaction with trans-cyclooctene-modified amino acids, the quenching effect is eliminated, and a green fluorescent signal is released, thereby dynamically monitoring the intracellular amino acid uptake process. CFSE-Tz can be applied to in vitro single-cell fluorescence imaging and studies related to amino acid metabolism in tumor cells (Ex = 495 nm, Em = 519 nm) [1] [2].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
