15 Results for "

ferric reducing

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "ferric reducing" in MCE Product Catalog:

Cat. No.: HY-113110
CAS No.: 19246-18-5
Purity:  99.96%
Synonyms: L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH
Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
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Cat. No.: HY-N12586
CAS No.: 603-17-8
Pheophytin a is a multi-target inhibitor, anticancer agent, antioxidant and antiviral agent. Pheophytin a directly binds to and inhibits HCV-NS3/4A protease (IC50=0.89 μM) to block viral replication. Pheophytin a also scavenges free radicals, reduces ferric ions, and exhibits cytotoxic activity against breast cancer cells. Pheophytin a effectively inhibits LPS-induced production of nitric oxide, prostaglandin E2, NOS2 and COX-2, as well as various pro-inflammatory cytokines, by downregulating the transcription levels of inflammatory mediators and blocking the ERK1/2 and STAT-1 pathways. In a low nerve growth factor environment, Pheophytin a also enhances ERK1/2 phosphorylation and synergistically promotes neurite outgrowth through MAPK pathway. Pheophytin a can be used to investigate the pathogenic mechanisms of diseases including chronic hepatitis C, sepsis, breast cancer and Alzheimer's disease .
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Cat. No.: HY-N6037
CAS No.: 2798-20-1
Gardenin B is a methoxyflavone compound and an inhibitor of USP7, ODC (IC50: 6.24 μg/mL), and Cathepsin D (IC50: 5.61 μg/mL). Gardenin B exhibits antioxidant and antitumor activities. Gardenin B shows IC50 values of 8.87 and 10.59 μg/mL for DPPH and NO scavenging, respectively, and also possesses ferric ion reducing ability. Additionally, Gardenin B can inhibit tumor cell proliferation, induce cell cycle arrest and apoptosis. Gardenin B can be used in cancer research .
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Cat. No.: HY-N2307A
CAS No.: 54383-28-7
Synonyms: (+)-Lirinidine
Lirinidine ((+)-Lirinidine) is an alkaloid isolated from the leaves of L. tulipifera and has antioxidant and anticancer activities. Lirinidine exhibits medium ferric reducing power activity and minor radical scavenging activity in vitro. Lirinidine can be used for cosmetic research .
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Cat. No.: HY-N9588
CAS No.: 22860-72-6
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .
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Cat. No.: HY-174867
CAS No.: 3091513-13-9
Target:  

PROTACs Ferroptosis

Research Areas:  

Cancer

AY-4 (Compound AY-4) is an efficient PROTAC degrader targeting FTH1 (Kd = 3.17 nM). AY-4 effectively upregulates the levels of ferrous (Fe 2+) and ferric (Fe 3+) ions in cells. AY-4 is a potential anticancer candidate compound that regulates iron homeostasis through ferritin degradation and enhances the efficacy of existing drugs. AY-4 can effectively reduce the level of FTH1 in breast cancer cells (Pink: FTH1 ligand AY-2 (HY-174871); Blue: E3 ligand Pomalidomide (HY-10984); Black: Linker, Pomalidomide-PEG3-acid (HY-174872)) .
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Cat. No.: HY-N7648
CAS No.: 5531-98-6
Synonyms: Atherospermine
Atherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria .
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Cat. No.: HY-113110R
CAS No.: 19246-18-5
Synonyms: L-Cysteinylglycine (Standard); Cys-Gly (Standard); H-Cys-Gly-OH (Standard)
Cysteinylglycine (Standard) is the analytical standard of Cysteinylglycine. This product is intended for research and analytical applications. Cysteinylglycine is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
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Cat. No.: HY-N6037R
CAS No.: 2798-20-1
Gardenin B (Standard) is the analytical standard of Gardenin B (HY-N6037). This product is intended for research and analytical applications. Gardenin B is a flavonoid isolated from Gardenia jasminoides. Gardenin B is a methoxyflavone compound and an inhibitor of USP7, ODC (IC50: 6.24 μg/mL), and Cathepsin D (IC50: 5.61 μg/mL). Gardenin B exhibits antioxidant and antitumor activities. Gardenin B shows IC50 values of 8.87 and 10.59 μg/mL for DPPH and NO scavenging, respectively, and also possesses ferric ion reducing ability. Additionally, Gardenin B can inhibit tumor cell proliferation, induce cell cycle arrest and apoptosis. Gardenin B can be used in cancer research .
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Cat. No.: HY-N10770
CAS No.: 1221762-70-4
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .
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Cat. No.: HY-N19331
CAS No.: 5989-43-5
Matricarin is a sesquiterpene lactone antioxidant with ferric ion reducing antioxidant power activity. Matricarin exhibits free radical scavenging activity. Matricarin induces growth inhibition. Matricarin can be used in the research of ovarian cancer and renal cancer .
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Cat. No.: HY-N7648A
CAS No.: 54749-97-2
Synonyms: Atherospermine hydrochloride
Atherosperminine (Atherospermine) hydrochloride is a phosphodiesterase inhibitor. Atherosperminine hydrochloride inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine hydrochloride scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine hydrochloride can be used for the research of malaria .
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Cat. No.: HY-184638
APTS Fe2O3 Nanoparticles (Aminated ferric oxide magnetic nanoparticles) are magnetic nanomaterials modified with amino functional groups using APTS. This material consists of a ferric oxide (Fe3O4) nanoparticle core and an amino (-NH2) surface modification layer. The aminated surface helps improve the biocompatibility of the nanoparticles and reduce cytotoxicity. The amino functional groups can be further chemically modified for coupling with biomolecules such as drugs, proteins, and nucleic acids. The amino functional groups undergo protonation at different pH values, resulting in different surface charges on the nanoparticles in different pH environments.
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Cat. No.: HY-N17215
CAS No.: 99523-99-6
Synonyms: 3,4,6-Trigalloylglucose
3,4,6-Tri-O-galloyl-D-glucose (3,4,6-Trigalloylglucose) is an α-amylase (porcine α-amylase IC50 = 334.6 μM; Ki = 307.5 μM) and α-glucosidase (yeast α-glucosidase IC50 = 46.5 μM; Ki = 39.9 μM) mixed type inhibitor. 3,4,6-Tri-O-galloyl-D-glucose exhibits free radical scavenging ability, ferric-reducing power, and antioxidant activity. 3,4,6-Tri-O-galloyl-D-glucose can be used for the research of diabetes .
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Cat. No.: HY-N17816
CAS No.: 571-72-2
Tambulin is an orally active flavonol compound found in Zanthoxylum armatum. Tambulin can inhibit cell proliferation, induce apoptosis and inhibit ROS production. Tambulin upregulates cleaved caspase-3, cleaved caspase-9, and Bax, downregulates Bcl-2 levels. Tambulin can stimulate glucose-dependent insulin secretion and induce endothelium-independent vasorelaxation. Tambulin binds to succinate dehydrogenase (SDH) (Ki = 11.02 μM) and shows significant ferric reducing power. Tambulin can enhances oxidative stress resistance, reduces, lipofuscin deposits, lipid levels, α-synuclein levels, improves locomotary behavior, and dopamine levels in in age-synchronized L1 hermaphrodite Caenorhabditis elegans models of ageing and Parkinson's disease. Tambulin can be used for the researches of Parkinson's disease, lung squamous cell carcinoma, and diabetes .
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