54749-97-2
Chemical Structure
Atherosperminine hydrochloride
Synonym(s): Atherospermine hydrochloride
- CAS No.: 54749-97-2
- Formula:C20H24ClNO2
- Molecular Weight:345.86
InChIKey: RGVLRZIFZIVJMN-UHFFFAOYSA-N
SMILES: CN(C)CCC1=C2C=CC3=CC=CC=C3C2=C(OC)C(OC)=C1.Cl
Biological Activity: Atherosperminine (Atherospermine) hydrochloride is a phosphodiesterase inhibitor. Atherosperminine hydrochloride inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine hydrochloride scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine hydrochloride can be used for the research of malaria[1][2].
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Atherosperminine hydrochloride | Atherosperminine (Atherospermine) hydrochloride is a phosphodiesterase inhibitor. Atherosperminine hydrochloride inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine hydrochloride scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine hydrochloride can be used for the research of malaria. | |||||||||||||||||||||
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- [1]. Nasrullah AA, et al. Antiplasmodial alkaloids from the bark of Cryptocarya nigra (Lauraceae). Molecules. 2013;18(7):8009-8017. Published 2013 Jul 8. [Content Brief]
- [2]. Lin CH, et al. The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens. Eur J Pharmacol. 1993;237(1):109-116. [Content Brief]
Keywords
