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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
geographic atrophy
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "geographic atrophy" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P3252A
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Cat. No.: HY-148457
CAS No.: 1613641-69-2
Synonyms: Izervay
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Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5, and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b, which forms the membrane attack complex (C5b-9), thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA .
Synonyms: IONIS-FB-LRx sodium; RG6299 sodium; ISIS 696844 sodium
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Sefaxersen sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). Sefaxersen sodium effectively reduces circulating levels of CFB, and can be used for geographic atrophy (GA) research .
Cat. No.: HY-148370
CAS No.: 2272975-74-1
Synonyms: IONIS-FB-LRx; RG6299; ISIS 696844
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Sefaxersen (IONIS-FB-LRx) is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). Sefaxersen effectively reduces circulating levels of CFB. Sefaxersen can be used for geographic atrophy (GA) research .
Cat. No.: HY-N0679S
CAS No.: 118139-36-9
Synonyms: ALK-001; Retinol acetate-d3; Vitamin A acetate-d3
Cat. No.: HY-106429
CAS No.: 627085-11-4
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OT-551 (free base) is a lipophilic, disubstituted hydroxylamine with antioxidant properties. OT-551 can be used as an eye drop and can be converted by intraocular esterases to its active metabolite, Tempol-H (TP-H). OT-551 can be utilized in geographic atrophy and macular degeneration research .
Cat. No.: HY-P991534
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Cat. No.: HY-P992142
CAS No.: 3050549-24-8
Synonyms: ANX-007
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
