2272983-11-4
2272983-11-4
Chemical Structure
Sefaxersen sodium
Synonym(s): IONIS-FB-LRx sodium; RG6299 sodium; ISIS 696844 sodium
- CAS No.: 2272983-11-4
- Formula:N/A
- Molecular Weight:8678.96 (free acid)
SMILES: [Sefaxersen sodium]
Biological Activity: Sefaxersen sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). Sefaxersen sodium effectively reduces circulating levels of CFB, and can be used for geographic atrophy (GA) research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sefaxersen sodium | 99.46% | Sefaxersen sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). Sefaxersen sodium effectively reduces circulating levels of CFB, and can be used for geographic atrophy (GA) research. | ||||||||||||||||||||
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References
- [1]. Dreismann AK, et al. Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway. Immunol Rev. 2022 Nov 12. [Content Brief]
- [2]. Mahmoudzadeh R, et al. Emerging treatments for geographic atrophy in age-related macular degeneration. Curr Opin Ophthalmol. 2021 May 1;32(3):294-300. [Content Brief]
Keywords
