34 Results for "

glycoprotein-IIb

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "glycoprotein-IIb" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-B0686
CAS No.: 188627-80-7
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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9
9 Publications Verification
Cat. No.: HY-B0686B
CAS No.: 881997-86-0
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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3
3 Cited Publications
Cat. No.: HY-P0074
CAS No.: 67869-62-9
Synonyms: Gly-Pro-Arg-Pro; Pefa 6003
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .
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3
3 Cited Publications
Cat. No.: HY-P0074A
CAS No.: 157009-81-9
Synonyms: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
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2
2 Cited Publications
Cat. No.: HY-P9934
CAS No.: 143653-53-6
Synonyms: C7E3

Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .
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1
1 Cited Publications
Cat. No.: HY-P77716
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: ITGA2B; Platelet Fibrinogen Receptor, Alpha Subunit; Prev. GP2B; Platelet glycoprotein IIb; GPIIb; AlphaIIb Protein; Integrin Alpha-IIb; glycoprotein IIb; PPP1R93; CD41 Antigen; CD41B; BDPLT16; CD41; BDPLT2; Integrin, Alpha 2b (Platelet glycoprotein IIb O
Species:  
Source:  
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Cat. No.: HY-146332
CAS No.: 104260-73-3
Target:  

P-selectin

Research Areas:  

Cardiovascular Disease

Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research .
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Cat. No.: HY-B0686A
CAS No.: 1248559-53-6
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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Cat. No.: HY-10305
CAS No.: 149820-74-6
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Xemilofiban is an orally active glycoprotein IIb/IIIa blocking agent. Xemilofiban inhibits platelet aggregation. Xemilofiban reduces the incidence of thrombosis .
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Cat. No.: HY-10309
CAS No.: 172927-65-0
Purity:  99.67%
Synonyms: RO 48-3657
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .
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Cat. No.: HY-10309R
CAS No.: 172927-65-0
Synonyms: RO 48-3657 (Standard)
Research Areas:  

Cardiovascular Disease

Sibrafiban (Standard) is the analytical standard of Sibrafiban. This product is intended for research and analytical applications. Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .
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Cat. No.: HY-101720
CAS No.: 148396-36-5
Synonyms: BIBU-52
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.
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Cat. No.: HY-101720A
Purity:  99.96%
Synonyms: BIBU-52 hydrochloride
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Fradafiban (BIBU-52) hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.
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Cat. No.: HY-10308
CAS No.: 149503-79-7
Target:  

Integrin

Research Areas:  

Metabolic Disease

Lefradafiban is an orally active glycoprotein IIb/IIIa receptor antagonist. Lefradafiban can be metabolized to its active form, Fradafiban, a non-peptide GP IIb/IIIa receptor antagonist .
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Cat. No.: HY-111348
CAS No.: 144412-49-7
Synonyms: Ro 44-9883
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Lamifiban is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban is promising for research of acute coronary syndromes .
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Cat. No.: HY-108881R
CAS No.: 2751-09-9
Synonyms: Triacetyloleandomycin (Standard)
Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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Cat. No.: HY-B0686BR
CAS No.: 881997-86-0
Research Areas:  

Cardiovascular Disease

Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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Cat. No.: HY-111348A
CAS No.: 144412-50-0
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Lamifiban TFA is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban TFA in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban TFA is promising for research of acute coronary syndromes .
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Cat. No.: HY-U00235
CAS No.: 180144-61-0
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively.
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Cat. No.: HY-126039
CAS No.: 168157-33-3
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

L-739758 is an antagonist for αIIbβ3 integrin (platelet glycoprotein IIb/IIIa). L-739758 acts as a peptidomimetic, binds to αIIbβ3 integrin by mimicking the interaction of the RGD (arginine-glycine-aspartic acid) motif, and is involved in the blood coagulation process. L-739758 inhibits platelet aggregation, and is used for thrombosis research .
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