157009-81-9
157009-81-9
Chemical Structure
GPRP acetate
Synonym(s): Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate
- CAS No.: 157009-81-9
- Formula:C20H35N7O7
- Molecular Weight:485.53
IUPAC Name: glycyl-L-prolyl-L-arginyl-L-proline compound with acetic acid (1:1)
InChIKey: ZYTSTPIIKNCGRE-QKWXXBCPSA-N
SMILES: CC(O)=O.O=C([C@H]1N(CCC1)C(CN)=O)N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(O)=O)=O
Biological Activity: GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GPRP acetate | 99.68% | GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). | ||||||||||||||||||||
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References
- [1]. Gallistl S, et al. Gly-pro-arg-pro (GPRP) enhances free thrombin. Thromb Res. 1995 Jun 15;78(6):547-50. [Content Brief]
- [2]. Hsieh KH, et, al. Fibrin Polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J Med Chem. 1981 Mar; 24(3): 322-7. [Content Brief]
- [3]. Zhang C, et al. Fibrinogen/AKT/Microfilament Axis Promotes Colitis by Enhancing Vascular Permeability. Cell Mol Gastroenterol Hepatol. 2021;11(3):683-696. [Content Brief]
