180144-61-0
180144-61-0
Chemical Structure
SR121566A
- CAS No.: 180144-61-0
- Formula:C20H25N5O4S
- Molecular Weight:431.51
IUPAC Name: 3-((4-(4-carbamimidoylphenyl)thiazol-2-yl)(1-(carboxymethyl)piperidin-4-yl)amino)propanoic acid
InChIKey: LYIQNVKSTSEEEG-UHFFFAOYSA-N
SMILES: O=C(O)CN1CCC(N(C2=NC(C3=CC=C(C(N)=N)C=C3)=CS2)CCC(O)=O)CC1
Biological Activity: SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively.
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SR121566A | SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively. | |||||||||||||||||||||
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Keywords
