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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
gravis
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "gravis" in MCE Product Catalog:
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3 Cited Publications
Synonyms: Eustigmin bromide; Neoserine bromide
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Neostigmine (Eustigmin) Bromide is an orally active and reversible cholinesterase inhibitor that acts on myasthenia gravis to prolong and intensify the muscarinic and nicotinic effects of acetylcholine. Neostigmine Bromide can be used in anesthesia to reverse the neuromuscular blockade produced by competitive neuromuscular blockers .
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Synonyms: ALXN2050; ACH 0145228; ACH-5228
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Vemircopan (ALXN2050) is an orally active complement factor D (FD) inhibitor. Vemircopan can be used in the research of diseases such as myasthenia gravis, lupus nephritis, IgA nephropathy, and paroxysmal nocturnal hemoglobinuria .
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2 Cited Publications
Cat. No.: HY-N5077
CAS No.: 18696-26-9
Category:
Alkaloids Plant Monophenols Neurological Disease Other Alkaloids Phenols Cruciferae Extract Disease Research Fields Inflammation/Immunology
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Alkaloids Plant Monophenols Other Alkaloids Phenols Cruciferae Extract Disease Research Fields Cancer
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Cat. No.: HY-147305
CAS No.: 1821402-21-4
Synonyms: ARGX-113
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Cat. No.: HY-P990706
CAS No.: 2490217-42-8
Synonyms: ALPN-303
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Cat. No.: HY-P99009
CAS No.: 2187430-05-1
Synonyms: RVT-1401; HBM9161; IMVT-1401
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Cat. No.: HY-P5766
CAS No.: 663154-30-1
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Edrophonium chloride is a short-acting acetylcholinesterase (AChE) inhibitor. Edrophonium chloride has Ki values of 0.2, 0.2, and 0.4 μM and IC50 values of 0.2, 0.05, and 0.5 μM for AChE in human erythrocytes, purified calf forebrain, and purified octopus brain, respectively. Edrophonium chloride can be used to detect early digitalis toxicity and in the study of myasthenia gravis .
Cat. No.: HY-P99365
CAS No.: 1803171-55-2
Synonyms: ALXN1210
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Cat. No.: HY-P991127
CAS No.: 2922766-89-8
Synonyms: DNTH103
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Synonyms: Distigmine dibromide
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Ubretid is a potent inhibitor of plasma cholinesterase. Ubretid therefore delays the hydrolysis of suxamethonium and prolongs its action, similar to the effects shown by other anticholinesterase agents, such as pyridostigmine and donepezil. Ubretid has the potential for the research of urinary retention prolongs the effect of suxamethonium. Ubretid is commonly prescribed for the research of myasthenia gravis and for difficulty in emptying the bladder .
Cat. No.: HY-P99638
CAS No.: 2456407-94-4
Synonyms: ALXN1720
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Gefurulimab (ALXN1720) is a high-affinity antibody inhibitor targeting complement protein C5, which can specifically bind to C5 and inhibit its cleavage into C5a and C5b. Gefurulimab can block the activation of the terminal complement pathway and reduce inflammatory damage. Gefurulimab can effectively reduce the formation of membrane attack complex (MAC) and has good pharmacokinetic properties. Gefurulimab can be used to study kidney and autoimmune diseases related to abnormal activation of the complement system, such as IgA nephropathy, lupus nephritis, and myasthenia gravis .
Cat. No.: HY-P5766A
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Cat. No.: HY-P990302
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ACG548B (compound 24) is a potent inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50s of 1.78 and 0.496 μM, respectively. ACG548B has higher AChE affinity and selectivity over BChE and ChoK (choline kinase). ACG548B can be uesd for the study of myasthenia gravis and neuromuscular blockade .
Cat. No.: HY-P990818
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AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 µM). AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis .
Cat. No.: HY-148412
CAS No.: 864021-55-6
Synonyms: EN101; ODN 7040; BL 7040
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Monarsen (EN101) is a synthetic 20-base antisense oligodeoxynucleotide directed against the human AChE gene. Monarsen is used in the study of Autoimmune myasthenia gravis (MG), a neuromuscular disorder caused by autoantibodies directed against the acetylcholine receptor (AChR).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
