2. Inhibitory Antibodies
  3. Nipocalimab

Nipocalimab  (Synonyms: M281)

Cat. No.: HY-P99037 Purity: 99.90%
COA

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Nipocalimab (M281) is a fully human, recombinant, aglycosylated IgG1 monoclonal antibody. Nipocalimab is a human deglycosylated IgG1 anti-FcRn monoclonal antibody that binds with picomolar affinity to Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6.

For research use only. We do not sell to patients.

Nipocalimab Chemical Structure

Nipocalimab Chemical Structure

CAS No. : 2211985-36-1

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Description

Nipocalimab (M281) is a fully human, recombinant, aglycosylated IgG1 monoclonal antibody. Nipocalimab is a human deglycosylated IgG1 anti-FcRn monoclonal antibody that binds with picomolar affinity to Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6[1][2].

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Nipocalimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.90%

COA (231 KB)

Handling Instructions (2659 KB)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nipocalimab2211985-36-1M281M 281M-281Othersaglycosylated IgG1 monoclonal antibodyIgG1 anti-FcRn monoclonal antibodyFc receptorFcRInhibitorinhibitorinhibit

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