663154-30-1
Chemical Structure
AChRα(97-116)
- CAS No.: 663154-30-1
- Formula:C106H162N24O30
- Molecular Weight:2252.56
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H]([C@H](O)C)C(NCC(N[C@H](C(N[C@H](C(O)=O)[C@@H](C)CC)=O)CC2=CN=CN2)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](C)NC([C@@H](NC([C@H](CC(O)=O)NC(CNC([C@@H](N)CC(O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O
Biological Activity: AChRα(97-116) is a synthetic peptide corresponding to the 97-116 region of the rat acetylcholine receptor α-subunit, and also an inducer of autoimmune diseases. AChRα(97-116) can be used in studies related to experimental autoimmune myasthenia gravis[1][2][3].
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AChRα(97-116) | 95.06% | AChRα(97-116) is a synthetic peptide corresponding to the 97-116 region of the rat acetylcholine receptor α-subunit, and also an inducer of autoimmune diseases. AChRα(97-116) can be used in studies related to experimental autoimmune myasthenia gravis. | ||||||||||||||||||||
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References
- [1]. Liu YM,et al. The effect of electroacupuncture on T cell responses in rats with experimental autoimmune encephalitis. J Neuroimmunol. 2010 Mar 30;220(1-2):25-33. [Content Brief]
- [2]. Hao Y, et al. Impaired cerebral microvascular endothelial cells integrity due to elevated dopamine in myasthenic model. J Neuroinflammation. 2024;21(1):10. Published 2024 Jan 4. [Content Brief]
- [3]. Cui YZ, et al. Enhancement of T Follicular Helper Cell-Mediated Humoral Immunity Reponses During Development of Experimental Autoimmune Myasthenia Gravis. Neurosci Bull. 2019;35(3):507-518. [Content Brief]