1. Peptides
  2. Obestatin(human)

Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane.

For research use only. We do not sell to patients.

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Obestatin(human) Chemical Structure

Obestatin(human) Chemical Structure

CAS No. : 1081110-72-6

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Based on 1 publication(s) in Google Scholar

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Description

Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane[1][2].

In Vitro

The primary structure of Obestatin(human) indicates that it only presented one lysine at position 10, which suggests that it cannot penetrate the cell membrane[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In adult male mice, intraperitoneal injection of Obestatin(human) suppresses food intake in a timeand dose-dependent manner[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2546.86

Formula

C116H176N32O33

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

FNAPFDVGIKLSGVQYQQHSQAL-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 1.96 mg/mL (0.77 mM; ultrasonic and adjust pH to 5 with HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Obestatin(human)
Cat. No.:
HY-P1421
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