2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. Anti-Human/Rat/Fish AChR Antibody (Mab35)

Anti-Human/Rat/Fish AChR Antibody (Mab35) 

Cat. No.: HY-P990302 Pureza: 95.00%
COA
SDS
Technical Support

Anti-Human/Rat/Fish AChR Antibody (Mab35) is an anti-human/rat/fish AChR IgG1 monoclonal antibody. Anti-Human/Rat/Fish AChR Antibody (Mab35) can attack the AChR of neuromuscular junctions. Anti-Human/Rat/Fish AChR Antibody (Mab35) can be used for the construction of myasthenia gravis models.

Para uso exclusivo en investigación. No vendemos a pacientes.

Anti-Human/Rat/Fish AChR Antibody (Mab35)

Anti-Human/Rat/Fish AChR Antibody (Mab35) Estructura química

Tamaño Precio Stock Cantidad
1 mg En stock
5 mg En stock
10 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

Anti-Human/Rat/Fish AChR Antibody (Mab35) Recomendaciones destacadas:

Anti-Human/Rat/Fish AChR Antibody (Mab35) Related Antibodies

Top Publications Citing Use of Products

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

Anti-Human/Rat/Fish AChR Antibody (Mab35) is an anti-human/rat/fish AChR IgG1 monoclonal antibody. Anti-Human/Rat/Fish AChR Antibody (Mab35) can attack the AChR of neuromuscular junctions. Anti-Human/Rat/Fish AChR Antibody (Mab35) can be used for the construction of myasthenia gravis models[1][2][3].

Isotype

Rat IgG1
Recommend Isotype Controls
Species Reactivity

Human/Rat/Fish
IC50 & Target

AChR
In Vitro

Anti-Human/Rat/Fish AChR Antibody (Mab35) (10 nM, 24 h) significantly inhibits the secretion of catecholamines in bovine adrenal chromaffin cells[2].
Anti-Human/Rat/Fish AChR Antibody (Mab35) specifically binds to the α1, α3, and α5 subunits of nAChR in TIB-175 hybridoma cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Human/Rat/Fish AChR Antibody (Mab35) Related Antibodies
In Vivo

Anti-Human/Rat/Fish AChR Antibody (Mab35) (1 mg/kg, i.v., on the seventh day after injection of C5 siRNA/LNP) successfully constructs the myasthenia gravis (MG) model in female Lewis rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Lewis rats[1]
Dosage: 1 mg/kg
Administration: Intravenous injection (i.v.), on the seventh day after injection of C5 siRNA/LNP
Result: Caused weight loss in rats.
Reduced fore limb grip strength, hindlimb weakness, and partial paralysis on days 8 and 9.
Gene ID

1138  [NCBI]

Accession

P30532 / NP_000736.2
Application

EAMG induction in rats; Immunofluorescence
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Human/Rat/Fish AChR Antibody (Mab35)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación

Purity: 95.00%

SDS (251 KB)

COA (232 KB)

Inhibitory Antibodies User Guide (603 KB)
Referencias
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Anti-Human/Rat/Fish AChR Antibody (Mab35) Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Human/Rat/Fish AChR Antibody (Mab35)nAChRNicotinic acetylcholine receptorsAChRmyasthenia gravisMGInhibitorinhibitorinhibit

Productos vistos recientemente:

Consulta en línea

Your information is safe with us. * Required Fields.

Nombre del producto

  

Requested Quantity *

Nombre del solicitante *

 

Saludo

Direcciòn del E-mail *

 

Número de teléfono *

Department

 

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

      

Observaciones

Consulta para venta a granel

Inquiry Information

Nombre del producto:
Anti-Human/Rat/Fish AChR Antibody (Mab35)
Cat. No.:
HY-P990302
Cantidad:
MCE Japan Authorized Agent:

Revisión del cliente

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nombre del producto

  

Lot #

Nombre del solicitante *

 

Direcciòn del E-mail *

Número de teléfono

 

Department *

Nombre de la Organizaciòn *

 

Country or Region *

Observaciones

SAFETY DATA SHEET (SDS)

English - EN (251 KB) Français - FR (251 KB) Deutsch - DE (251 KB) Norwegian - NO (251 KB) Español - ES (251 KB) Swedish - SV (251 KB) Italian - IT (251 KB) Korean - KR (251 KB) Portuguese - PT (251 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.